Table 1 Cytotoxicity of AgNPs in the study groups after 24 hours, 3 and 7 days

24 hours

Mean (SD)

7.26 (10.89)

3.99 (8.10)

5.13 (9.22)

1.44 (4.69)

0.54 (1.24)

X² = 6.032

(0.197)

Median (IQR)

1.00 (21.60)

0.78 (1.93)

0.52 (7.50)

−0.11 (1.99)

0.51 (1.45)

3 days

Mean (SD)

40.32 (2.92)^a,b

37.43 (2.61)^b,c

34.46 (3.24)^c

33.26 (3.19)^c

35.36 (4.06)^c

F = 6.557 (< 0.001*)

Median (IQR)

40.80 (4.66)

38.22 (4.90)

33.49 (4.05)

32.49 (4.85)

35.44 (7.25)

7 days

Mean (SD)

32.11 (2.55)^a

25.26 (2.63)^b

24.61 (3.21)^b

23.96 (2.44)^b

24.88 (3.09)^b

F = 2.897 (< 0.001*)

Median (IQR)

32.01 (4.65)

25.66 (3.74)

23.98 (5.15)

23.39 (4.37)

25.35 (4.77)

X² = 29.398 (< 0.001*)

X² = 27.657 (< 0.001*)

X² = 28.209 (< 0.001*)

X² = 29.562 (< 0.001*)

X² = 28.418 (< 0.001*)

P₁ < 0.001*

P₁ < 0.001*

P₁ < 0.001*

P₁ < 0.001*

P₁ < 0.001*

P₂ = 0.005*

P₂ = 0.006*

P₂ = 0.009*

P₂ = 0.005*

P₂ = 0.004*

P₃ = 0.231

P₃ = 0.228

P₃ = 0.181

P₃ = 0.210

P₃ = 0.263