Variable | Unadjusted1 | Adjusted | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Model 12 | Model 23 | Model 34 | |||||||||||
IRR5 | 95% CI | P-value | IRR | 95% CI | P-value | IRR | 95% CI | P-value | IRR | 95% CI | P-value | ||
Frequency of pregnancy | 4 ≤ | 1.34 | 1.21–1.48 | < 0.001 | 1.07 | 0.96–1.18 | 0.21 | 1.13 | 1.02–1.26 | 0.02 | 1.12 | 1.01–1.24 | 0.04 |
3 | 1.04 | 0.93–1.15 | 0.49 | 1.07 | 0.96–1.19 | 0.2 | 1.11 | 0.99–1.23 | 0.07 | 1.09 | 0.98–1.22 | 0.10 | |
2 | 0.94 | 0.84–1.05 | 0.27 | 1.05 | 0.94–1.17 | 0.34 | 1.08 | 0.97–1.21 | 0.16 | 1.07 | 0.96–1.19 | 0.21 | |
1 | 0.9 | 0.78–1.04 | 0.18 | 1 | 0.87–1.16 | 0.96 | 1.01 | 0.87–1.16 | 0.95 | 1 | 1.86–1.16 | 0.99 | |
0 | Reference | ||||||||||||
Age at the onset of menstrual (years) | Early (12>) | 1.06 | 0.98–1.16 | 0.15 | 0.99 | 0.91–1.08 | 0.91 | 1.01 | 0.93–1.09 | 0.84 | 1.01 | 0.93–1.09 | 0.86 |
Late (14<) | 1.12 | 1.07–1.18 | < 0.001 | 1.01 | 0.96–1.06 | 0.77 | 1.02 | 0.97–1.07 | 0.34 | 1.03 | 0.98–1.08 | 0.25 | |
Normal (12–14) | Reference | ||||||||||||
Age at the onset of menopause (years) | Precursor (< 40) | 0.95 | 0.83–1.1 | 0.51 | 0.98 | 0.85–1.14 | 0.83 | 0.98 | 0.85–1.13 | 0.81 | 0.98 | 0.85–1.13 | 0.81 |
Early (40–45) | 1 | 0.93–1.08 | 0.99 | 1 | 0.93–1.08 | 0.95 | 1.01 | 0.94–1.09 | 0.77 | 1.01 | 0.94–1.09 | 0.75 | |
Normal (> 45) | Reference | ||||||||||||
Age at first pregnancy (years) | 40–49 | 0.95 | 0.65–1.39 | 0.78 | 0.89 | 0.61–32/1 | 0.58 | 0.9 | 0.61–1.32 | 0.59 | 0.9 | 0.62–1.32 | 0.6 |
30–39 | 0.93 | 0.83–1.03 | 0.17 | 0.98 | 0.88–1.09 | 0.75 | 0.96 | 0.86–1.08 | 0.51 | 0.97 | 0.86–1.08 | 0.53 | |
10–19 | 1.1 | 1.05–1.16 | < 0.001 | 1.01 | 0.96–1.06 | 0.71 | 1.01 | 0.97–1.07 | 0.55 | 1.01 | 0.96–1.06 | 0.76 | |
20–29 | Reference |