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Fig. 4 | BMC Oral Health

Fig. 4

From: BACH1 regulates the proliferation and odontoblastic differentiation of human dental pulp stem cells

Fig. 4

The downregulation of BACH1 impeded the proliferation and induced cell cycle arrest of hDPSCs in vitro. a The effect of BACH1 silencing on the cell proliferation of hDPSCs was determined by CCK-8 assay. BACH1 silencing group (LV-shBACH1) and control group (LC-NC). b EdU assay for cell proliferation. Red, EdU-positive cells; Blue, Hoescht-stained cells. The percentage of EdU-positive cells in the LV-shBACH1 and LC-NC was recorded. Scale bar = 50 µm. c Percentage of cell cycle distribution tested by flow cytometry. Statistically significant compared to the LV-NC group. *P < 0.05, **P < 0.01, ***P < 0.001

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