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Table 1 Background characteristics, applied examination and assessment and the targeted primary outcomes

From: Dental caries at enamel and dentine level among European adolescents – a systematic review and meta-analysis

Background characteristics

Examination and Assessment

Primary outcomes

First Author,

Publication year

Year of exam

Country

Level

Study design

Sample size (N)

Total

F: Female M:

Male

Socio-economic status/

-position (SES/SEP)

Immigrant (IM)

 + : reported

− : not reported

Age

(yrs)

Diagnostic

method (ref.)

BW

(Yes/No)

Calibration (Yes/No)

Examiners

(N)

Caries prevalence

(%)

(D(M)FS > 0

or D(M)FT > 0)

1: enamel level

2: dentine level

Caries experience

Mean DeS

Mean D(M)FS

or Mean DeT

Mean D(M)FT with enamel caries included

Proportion

(DeS/D(M)FS

or

Proportion

(DeT/D(M)FT

Caries distribution

 + : reported

−: not reported

Full mouth caries examination

Saethre-Sundli HB et al. [49]

2020

2014 Norway

Subnational

Cohort

Exam. at Follow-up 2014

3,282

F: 1586 M: 1696

 + :

Parental education Family status National background

Mean age:

12.1

(SD: 0.5)

Amarante E et al. [71]

Yes

Yes

91

1: 58

2: 32

DeS: 1.35

DMFS: 2.15 (SD: 3.4)

0.63

+

Jacobsen ID et al. [43]

2016

2010–2011

Norway

Subnational

Cross-sectional

869

F: 420

M: 449

 + :

National background

Parental education

Family status

16

Amarante et al. [71]

Yes

Yes

1

1: 94

2: 83

-

-

-

David J et al. [59]

2006

1993 Baseline

Cohort

Exam. at Baseline

159

 + :

Mothers’ education

12

Amarante E et al. [71]

Yes

Yes

5

1: 90

2: 63

DeS: 6.2 (SD: 5.9)

DMFS: 8.9 (SD: 7.8)

0.70

 + 

1999

Follow-up

Norway

Community

Exam. at Follow-up

112

F: 56

M: 56

18

Amarante E et al. [71]

Yes

Yes

1

1: 99

2: 92

DeS: 4.4 (SD: 4.5)

DMFS: 13.1 (SD: 11.4)

0.34

Karlsson F et al

[51]

2019

2009

Baseline

Cohort

Exam. at Baseline

159

F: 82

M: 77

-

12

Socialstyrelsen, 1988 [72]

BW on indication only

No

-: number examiners not reported

1: 48

2: not reported

*DeS: 1.1 (SD: 2.3)

DFS: 1.8 (SD: 2.9)

*0.61

-

2014

Follow-up

Sweden

Community

Exam. at Follow-up

159

F: 82

M: 77

17

1: 55

2: not reported

*DeS: 2.6 (SD: 4.2)

DFS: 4.5 (SD: 6.1)

*0.58

Koch G et al. [54]

2017

2013

Sweden

Community

Cross-sectional

101

F: 49

M: 52

-

15

Koch G [73]

Yes

Yes

3

1: 57

2: not reported

DFS: 3.0 (CI: 1.9–4.1)

-

 + 

Jacobssen B et al. [74]

2011

2003

Sweden

Community

Cross-sectional

85

IM:

11

 + :

Education

National background

15

Koch G

[73]

Yes

Yes

8

1: 81

2: not reported

IM:

1: 100

2: not reported

-

IM

DFS: 11.8 (CI: 5.4–18.3)

-

-

Non IM:

74

Non IM:

1: 78

2: not reported

Non IM:

DFS: 5.5 (CI: 3.9–7.1)

Hugoson A al. [55]

2008

2003 Sweden

Community

Cross-sectional

96

F: 51

M: 45

-

15

Koch G [73]

Yes

Yes

10

1: 80

2: not reported

DeS: 4.7

DFS: 6.4 (CI: 4.8–8.0)

0.73

 + 

Agustsdottir H et al. [50]

2010

2004–2005

Iceland

National

Cross-sectional

757

-

12

ICDAS

Yes

Yes

1

1: 85

2: 66

*DeS: 5.67 (SE:0.47)

DMFS: 8.77 (SE:0.64)

*0.65

 + 

750

15

1: 94

2: 80

*DeS: 10.66 (SE: 0.80) (

DMFS: 17.00 (SE:1.10)

*0.63

Splieth CH et al.[45]

2019

2016

Germany

National

Cross-sectional

55,002

 + :

School type

Class level

12

WHO [25] + initial caries lesions (IT)

No

Yes

482

1: 34

2: 21

DeT: 0.52

DMFT: 0.96

0.54

 + 

Jablonski-Momeni A et

al. [46]

2014

2009–2010

Germany

Subnational

Cross-sectional

2 regions (969)

Region

1: 525

 + :

Mothers’ education

National background

12

ICDAS

No

Yes

1: 43

2: 23

*DeS: 0.77

DFS: 1.61

*0.48

 + 

Region

2: 444

Yes

1

1: 50

2: 17

*DeS: 1.7

DFS: 2.80

*0.61

Wang X et al. [37]

2021

2013

England, Wales, Northern Ireland

National

Cross-sectional(analyses of clusters)

2160

Cluster analyses:

 + :

School type

Free school meals eligibility

Deprivation Index (IMD)

Region category

National background

15

ICDAS [75]

No

From dental records (available data)

1: not reported

2: not reported

DeS: 1.73

DMFS: 4.39

CI: 3.60- 5.18)

0.39

 + 

Wang X et al. [21]

2021

2013

England, Wales, Northern Ireland

National

Cross-sectional

2532

 + :

School type

Free school meal eligibility

Deprivation Index (IMD)

Region category

National background

12

ICDAS

No

Yes

75

1: 65

2: 45

DeS: 1.61

DMFS: 3.91 (SD: 5.90)

0.41

 + 

2418

15

1: 73

2: 59

DeS: 2.02

DMFS: 5.94 (SD: 8.04)

0.34

Vernazza CR et al. [38]

2016

2013 England, Wales, Norhern Ireland

National

Cross-sectional

9866 (number included also 5-, 8- year-olds)

 + :

Free school meals eligibility

Gender

12

ICDAS

No

Yes

75

1: 57

2: approximately 33

DeT: 1.2

DMFT: 2.0

0.60

-

15

1: 63

2: approximately 50

DeT: 1.5

DMFT: 2.9

0.52

Baciu D et al. [52]

2015

2011

UK

Community (n = 5)

Cross-sectional

592

F: 323

M: 269

 + :

Regions

Mean age: 12.3

ICDAS

No

Yes

1

1: 83

2:76

*DeS: 1.71 (SD: 2.10)

DMFS: 6.78 (SD: 7.25)

*0.25

-

Maldupa I et al. [48]

2021

2016 Latvia

National

Cross-sectional

2138

F: 1031

M: 1107

 + :

Region

Socio-economy

(Family Affluence Scale (FAS))

12

ICDAS II

No

Yes

7

1: 99

2: 80

*DeS: 12.6 (SD: 10.5)

DMFS: 17.6 (SD: 13.2)

*0.72

 + 

Deery C et al. [76]

2000

1997 Latvia

Community

Cross-sectional

182

F: 102

M: 80

-

Mean age: 13.3 (range: 10.6–15.7)

Deery et al. [77]

No

Visual examination (CVE)

Yes

1

1: not reported

2: 99.5

DeS:

10.38 (SD: 11.68)

DMFS: 22.65

0.46

-

Almerich-Torres T et al. [41]

2020

2018

Spain

Community

Cross-sectional

632

 + :

Social class by parental occupation

12

ICDAS II

No

Yes

3

1: not reported

2: 30

DeS: 1.67

DMFS: 2.41

0.69

-

534

15

1: not reported

2: 45

DeS: 2.03 DMFS: 3.39

0.60

Almerich-Torres T et al. [39]

2017

2010

Spain

Community

Cross-sectional

409

F: 216

M: 193

 + :

Social class by parental occupation

(Domingo et al.)

12

ICDAS II

No

Yes

3

1: not reported

2: not reported

DeT: 2.57

DMFT: 3.44

(CI: 3.08–3.80)

0.75

-

433

F: 226

M: 207

15

DeT: 3.66

DMFT: 4.74

(CI: 4.37–5.11)

0.77

Almerich-Silla JM et al. [40]

2014

2010 Spain

Community

Cross-sectional

1373

 + :

Social class by parental occupation (Domingo et al.)

12

ICDAS II

No

Yes

6

1: 77

2: 38

DeS: 3.18

DMFS: 4.45 (CI: 3.96–4.93)

0.71

-

15

1: 85

2: 44

DeS: 4.23

DMFS: 5.87 (CI: 5.36–6.37)

0.72

Calado R et al. [47]

2017

2009

Portugal

National

Cross-sectional

1309

 + :

Mothers’ occupation and education

Area of residence

Region

12

ICDAS

No

Yes

24

1: 76

2: 47

DeS: 3.40 (SD: 0.17)

DMFS: 8.61 (SD: 0.34)

0.39

 + 

1075

18

No

1: 89

2: 68

DeS: 4.36 (SD: 0.20)

DMFS: 16.64 (SD: 0.51)

0.26

Campus G et al. [60]

2020

2017

Italy

National

Cross-sectional

7064

F: 3605

M: 3459

 + :

Income inequality and Unemployment rate

Parental education

Working status

National background

12

ICDAS [78]

No

Yes

4

1: 70

2: not reported

DeT: 2.29

DFT: 3.71

0.62

-

Diamanti I et al. [57]

2021

2013 Greece

National

Cross-sectional

1243

F: 631

M: 612

 + :

Urban/rural area of residence

Parental education

12

ICDAS II

No

Yes

10

1: 72

2: 52

1: F: 74

1: M: 69

2: F: 54

2: M: 50

-

*F:

DeT: 1.8 (SD: 2.5)

DMFT: 3.6

*M:

DeT: 1.7 (SD: 2.6)

DMFT: 3.1

*F: 0.50

*M: 0.55

-

1227

F: 658

M: 569

15

1: 82

2: 66

1: F: 79

1: M:86

2: F: 68

2: M: 63

-

*F:

DeT: 2.6 (SD: 3.2)

DMFT: 5.2

*M:

DeT: 2.4 (SD: 3.1)

DMFT: 4.7

*F: 0.50

*M: 0.51

Partial mouth caries examination (proximal surfaces of posterior teeth). One study also included occlusal surfaces

Jacobsen ID et al

2019 [42]

Jacobsen ID et al. Norway. Details under full mouth caries examination

1: 84

2: not reported

DeAS: 5.8 (SD: 5.0)

-

-

Bergström EK et al

[53]

2019

2005-

Cohort

Controls: Exam. at Baseline

Control group:

10,160

F: 4923

M: 5237

 + : Geographical area

12

Gröndahl et al. [80]

Not reported

Not reported

1: not reported

2: not reported

DeAS: 0.86

DAFS: 1.08

0.80

-

2008 Sweden

Subnational

Controls: Exam. at Follow-up

15

DeAS:2.19

DAFS: 2.88

0.76

Alm A et al. [56]

2006

2002 Sweden

Community

Cohort

Exam. at Follow-up

568

F: 286

M: 282

???

 + :

Socio-economic regions

15

Socialstyrelsen [72]

Yes

Yes

1

1: 67

2: 22

DeAS: 2.78 (range 0–18)

DAFS: 3.23 (Range:0–20)

0.86

-

**Koch G et al

[54] 2017

2013 Jönköping study, Sweden. Details under full mouth caries examination

0.80–0.90

 

Hugoson A et al. [55] 2008

2003 Jönköping study, Sweden. Details under full mouth caries examination

0.80–0.90

 

Sköld UM et al. [79]

2005

1999–2003

Sweden

Community

Cohort Controls: Exam. at Baseline

94

-

13

Gröndahl et al. [80]

Yes

No

2

1: not reported

2: not reported

DAFS: 1.45 (SD: 2.17)

-

-

Controls: Exam. at Follow up

16

1: not reported

2: not reported

DA.FS: 3.29 (SD: 4.45)

 

Jacobsson B et al. [81]

2005

2003

Sweden

Community

Cross-sectional

117

IM: 51

F: 27

M: 24

 + 

National background

15

Koch [73]

Yes

No

4

1: 74

2: 44

1: IM: 76

2: IM: 47

IM:

DeAS: 5.5 (CI: 4.0–7.0)

DA.FS: 6.5 (CI: 4.7–8.2)

0.85

-

Non IM: 66

F: 40

M: 26

1: Non IM: 74

2: Non IM: 42

Non IM:

DeAS: 3.3 (CI: 2.3–4.4)

DA.FS:: 4.0 (CI: 2.9–5.4)

0.83

Lith A et al. [82]

2002

1992–1993 Sweden

Community

Cross-sectional data

From dental records

285

 + :

Income and education exceeded the average Swedish citizen

17

Also occlusal lesions

Gröndahl et al. [80]

BW on indication only

Yes

-: number examiners not reported

1: 93

2: 84

-

-

 + 

Gustafsson A et al. [83]

2000

1993

Cohort

Exam. at

Baseline

93

Analyzed

67

F: 34

M: 33

-

14

Gustafson et al. [83]

Yes

Yes

2

1: 69

1: F: 76

1: M: 62

2: not reported

-

F:

DeAS: 4.2 (SD: 5.5)

DA.FS: 4.82

M:

DeAS: 2.9 (SD: 43.9)

DAlFS: 3.62

-

F: 0.87

M: 0.80

-

1998 Sweden

Community

Exam. at Follow-up

Analyzed

66

F: 33

M: 33

19

1: 92

1: F. 91

1: M: 94

2: not reported

-

F:

DeAS: 7.0 (SD: 4.7)

DA.FS: 9.7

M:

DeAS: 6.1 (SD: 4.7)

DAFS: 10.6

-

F: 0.72

M: 0.58

Pooerterman JHG et al

[84]

2003

1990

Cohort

From radiographs

121

-

14

Poorterman JHG. [85]

Yes

Yes

2

1: 86

2: not reported

DeAS:2.7 (SD: 3.1)

DA.FS: 3.73

0.72

-

1993

The Netherlands

Community

From radiographs

311

17

1: 88

2: not reported

DeAS: 3.8 (SD: 1.1)

DA.FS: 7.0

0.54

  1. The first part of the table consists of publications based on full mouth caries examination and the second one, on articles from partial caries examination (both places arranged after country of origin). Within these sections, the publications are presented consecutively according to publication date
  2. DeS: Surfaces with enamel caries (without– and with cavitation). DeAS: Proximal (approximal) DeS. DeT: Teeth with enamel caries (without– and with cavitation). D(M)FS: decayed (enamel and dentine caries)/(missed)/filled permanent surfaces. D(M)FT: decayed (enamel and dentine caries)/(missed)/filled permanent teeth. In many studies the M-component is not counted because no or almost no teeth were extracted due to caries. If available surface level index, this the one which is denoted in the table. DA(M)FS: decayed (enamel and dentine caries)/(missed)/filled approximal surfaces. Measures of variability (e.g. SD) are lacking in those cases components of mean caries experience have been calculated. Dental caries activity was not assessed
  3. (*) In case that enamel caries omits cavitated lesions in enamel and as such underscores the DeS/ DeT component
  4. (**) Article denoted in both categories; full mouth- and partial caries examination