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Table 5 Incidence and incidence rate ratios of visits for oral ulceration and temporomandibular joint disorders in the rheumatoid arthritis cohort and the comparison cohort

From: Increased dental visits in patients with rheumatoid arthritis: a secondary cohort analysis of population based claims data

Disorder

Age group (years)

Rheumatoid arthritis cohort

Comparison cohort

IRR (95% CI)

aIRR (95% CI)

(ICD-9-CM)

No. of patient

Person-years

Incidence

No. of patient

Person-years

Incidence

p value

P value

Oral ulcerationa (528.2)

 

Overall

222

7057

31.46

1734

70,434

24.62

1.28 (1.11–1.47)

0.001

1.24 (1.08–1.44)0.003

 

Sex

 

 Male

34

1539

22.09

351

15,880

22.10

1.00 (0.70–1.42)

0.999

1.05 (0.73–1.50)

0.804

 

 Female

188

5518

34.07

1383

54,554

25.35

1.34 (1.15–1.56)

< 0.001

1.29 (1.10–1.51)

0.002

 

Age group (years)

 

 20–54

121

4117

29.39

934

41,241

22.65

1.30 (1.07–1.57)

0.007

1.30 (1.06–1.58)

0.011

 

 > 55

101

2940

34.35

800

29,193

27.40

1.25 (1.02–1.54)

0.032

1.21 (0.98–1.50)

0.083

Temporomandibular joint disordersb (524.6)

 

Overall

18

7697

2.34

117

76,580

1.53

1.53 (0.93–2.51)

0.093

1.31 (0.77–2.23)

0.320

 

Sex

 

 Male

2

1660

1.20

23

17,083

1.35

0.90 (0.21–3.80)

0.881

0.79 (0.18–3.42)

0.750

 

 Female

16

6037

2.65

94

59,497

1.58

1.68 (0.99–2.85)

0.056

1.33 (0.75–2.36)

0.327

 

Age group (years)

 

 20–54

11

4448

2.47

70

44,502

1.57

1.57 (0.83–2.97)

0.163

1.40 (0.72–2.76)

0.323

 

 > 55

7

3249

2.15

47

32,078

1.47

1.47 (0.66–3.25)

0.341

1.24 (0.52–2.96)

0.630

  1. Adjusted for age, sex, socioeconomic status, geographic region, hypertension, diabetes, congestive heart failure, chronic pulmonary disease, cancer, dyslipidemia, coronary artery disease, prior myocardial infarction, peripheral vascular disease, cerebrovascular disease, dementia, musculoskeletal disorders, peptic ulcer disease, chronic kidney disease, and liver disease
  2. aIRR, adjusted incidence rate ratio; ICD-9-CM, International Classification of Diseases, Ninth revision, clinical modification; IRR, incidence rate ratio
  3. aPatients who were diagnosed with oral ulceration within 90 days before the index date were excluded and 1326 patients with rheumatoid arthritis and 13,275 controls were included in the analysis
  4. bPatients who were diagnosed with temporomandibular joint disorders within 90 days before the index date were excluded and 1302 patients with rheumatoid arthritis and 13,229 controls were included in the analysis