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Fig. 3 | BMC Oral Health

Fig. 3

From: Promotion of the resistance of human oral epithelial cells to herpes simplex virus type I infection via N6-methyladenosine modification

Fig. 3

Interfering with ALKBH5 or FTO can promote HSV-1-induced expression of type I interferon. A Knockdown of ALKBH5 and FTO using siRNA in HIOEC cells. B Knockdown of ALKBH5 and FTO increased m6A modification of RNA in HIOEC cells. C Knockdown of ALKBH5 and FTO activated the STING signaling pathway in HIOEC cells. D Knockdown of ALKBH5 and FTO increased mRNA expression levels of IFNα, IFNβ, ISG15 and CXCL10 in HIOEC cells. **P < 0.01

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BMC Oral Health

ISSN: 1472-6831

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