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Fig. 2 | BMC Oral Health

Fig. 2

From: Human salivary protein-derived peptides specific-salivary SIgA antibodies enhanced by nasal double DNA adjuvant in mice play an essential role in preventing Porphyromonas gingivalis colonization: an in-vitro study

Fig. 2

Salivary SIgA Ab responses to stat23 or prp21 peptide in mice. (A) Salivary SIgA Ab responses to stat23 or prp21 in mice given nasally single Ags with/without dDA. (B) Salivary stat23 or prp21 specific-SIgA Ab in mice given nasally double Ags with/without dDA. The levels of anti-peptide SIgA Abs in saliva were determined by the respective peptide Ag-specific ELISA assay. The values are presented as the median and interquartile range (the first quartile—1.5 IQR, the 3rd quartile + 1.5 IQR) of 15 mice in each group and were compared via two-tailed non-paired Mann–Whitney U-tests. *p < 0.05, **p < 0.01 vs. mice immunized with peptide Ag alone without dDA (dDA (-))

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