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Table 1 The numbers of HSPs-derived stat23- or prp21-specific SIgA AFCs in mice administered nasally single Ag (stat23 or prp21) with/without dDA

From: Human salivary protein-derived peptides specific-salivary SIgA antibodies enhanced by nasal double DNA adjuvant in mice play an essential role in preventing Porphyromonas gingivalis colonization: an in-vitro study

Mucosal inductive or effective tissues

Given prp21Ags

stat23

 

stat23-Specific SIgA AFCs

prp21-specific SIgA AFCs (in 106 mononuclear cells) (in 106 mononuclear cells)

dDA

 + 

−

 + 

−

Salivary glands

NALT

 

*14.6 ± 0.9

4.5 ± 0.5

*17.8 ± 1.5

7.8 ± 0.2

PGLNs

 

8.4 ± 1.3

4.1 ± 0.5

9.2 ± 0.7

5.9 ± 0.8

NPs

 

*162 ± 23

16 ± 4.6

*132 ± 27

23 ± 5.4

SMGs

 

*16.9 ± 3.3

5.4 ± 1.3

*25.1 ± 4.9

6.6 ± 1.7

SLGs

 

*25.8 ± 4.3

14.7 ± 5.9

*35.3 ± 5.7

12.7 ± 4.8

PGs

 

9.8 ± 3.1

5.4 ± 0.8

8.2 ± 3.0

5.1 ± 0.6