Fig. 7

Histopathological examination of mucormycosis (microscopic view). A Bone and sinus tissue (100× magnification, H&E*): Area of acute inflammation and fungal forms infiltration arteries (arrow); B Sinus specimen (400× magnification, H&E*): Colonies of fungal spores and non-septate hyphae invaded the lumen of a blood vessel, causing thrombosis (arrow); C Sinus tissue (400× magnification, PAS**): Multinucleated giant cells with a numerous PAS-positive fragments in the cytoplasm (arrow); D Sinus section (100× magnification, GMS***): Intravascular invasion by fungal hyphae (arrow); E Sinus tissue (400× magnification, PAS**): Non septate wide branched hyphae (arrow); F Sinus tissue (400× magnification, PAS**): Numerous fungal hyphae which were aseptate, broad with obtuse angle branching, and without spore formation (arrow). *H&E = Hematoxylin and Eosin stain. **PAS = Periodic acid-Schiff stain. ***GMS = Gomori methenamine-silver stain