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Fig. 3 | BMC Oral Health

Fig. 3

From: Oridonin alleviates the inhibitory effect of lipopolysaccharide on the proliferation and osteogenic potential of periodontal ligament stem cells by inhibiting endoplasmic reticulum stress and NF-κB/NLRP3 inflammasome signaling

Fig. 3

Oridonin alleviated the inhibitory effect of lipopolysaccharide (LPS) on the proliferation and osteogenic differentiation of hPDLSCs. A MTT to detect the proliferation rate of hPDLSCs cells in each group; B-D, ALP staining (B/D) and alizarin red staining (C/E) to assess ALP concentration and calcium nodule formation in hPDLSCs cells, respectively; FH, qRT-PCR to detect the expression level of osteogenesis-related genes Runx2 (F), OPN (G) and Col-1 (H) in hPDLSCs cells in each group, **P < 0.01 versus CTRL group, #P < 0.05 and ##P < 0.01 versus LPS group

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