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Table 1 Clinicopathological information of patient cohort

From: Exploring the microbiome of oral epithelial dysplasia as a predictor of malignant progression

 

All

(%)£

No progression*

(%)£

Progression*

(%)£

Total

n = 90

n = 60

n = 30

Length of follow-up Median months (range)

83.8 (12.9 to 181.4)

85.3 (18.0 to 172.5)

73.7 (12.9 ± 181.4)

Age at diagnosis

Mean (years ± SD)

60.2 ± 10.4

60.6 ± 10.2

59.3 ± 10.9

Sex

 Male

42 (47)

28 (47)

14 (47)

 Female

48 (53)

32 (53)

16 (53)

Ethnicity

 White

73 (81)

49 (82)

24 (80)

 Asian

10 (11)

6 (10)

4 (13)

 South or East Asian

5 (6)

5 (8)

0 (0)

 Other

2 (2)

0 (0)

2 (7)

Smoking historya

 Never

54 (60)

35 (58)

19 (63)

 Ever

36 (40)

25 (42)

11 (37)

Alcohol consumptionb

 Non/light

81 (90)

54 (90)

27 (90)

 Heavy

9 (10)

6 (10)

3 (10)

Lesion sitec

 Low Risk

12 (13)

8 (13)

4 (13)

 High Risk

78 (87)

52 (87)

26 (87)

Grade of dysplasia

 Mild dysplasia

42 (47)

33 (55)

9 (30)

 Moderate dysplasia

48 (53)

27 (45)

21 (70)

Time to progression category

 < 1 year

-

-

5 (17)

 1 – 2 years

5 (17)

 2 – 3 years

5 (17)

 3 – 4 years

6 (20)

 4 – 6 years

5 (17)

 > 6 years

4 (13)

  1. *Progression = progression to severe dysplasia, carcinoma in situ, or squamous cell carcinoma; No progression = no progression to severe dysplasia, carcinoma in situ, or squamous cell carcinoma after a minimum of five years of follow-up
  2. £Column percentage reported
  3. aNever smoker < 100 cigarettes in lifetime; Ever smoker > 100 cigarettes in lifetime
  4. bHeavy alcohol consumption is defined as consumption of more than 14 drinks per week for females and 21 drinks per week for men. One alcoholic drink was defined as 8 oz of beer, 5 oz of wine or 1 oz of spirits
  5. cHigh Risk = floor of mouth, soft palate, and tongue; Low Risk = all other sites