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Table 1 The characteristics of the included literature

From: Sedative and adverse effect comparison between oral midazolam and nitrous oxide inhalation in tooth extraction: a meta-analysis

First Author

Year

Country

Number of patients

Age

Therapeutic Drug

Study Designs

Literature Quality

Evaluation Indicators

K. E. Wilson [10]

2006

United Kingdom

35

5–10(years)

Midazolam Nitrous Oxide

Randomized controlled trial

HQ

Sedation and Analgesia Success Rate Adverse Effects Rate

K. E. Wilson [11]

2002

United Kingdom

44

10–16 (years)

Midazolam Nitrous Oxide

Randomized controlled trial

HQ

Sedation and Analgesia Success Rate Adverse Effects Rate

K. E. Wilson [12]

2002

United Kingdom

26

10–16 (years)

Midazolam Nitrous Oxide

Randomized controlled trial

HQ

Sedation and Analgesia Success Rate Adverse Effects Rate

Tian Xiaohua [13]

2015

China

67

4–14 (years)

Midazolam Nitrous Oxide

The cohort study

HQ

Sedation and Analgesia Success Rate Adverse Effects Rate

Shi Xiangjun [14]

2005

China

17

2–30 (years)

Midazolam

The cohort study

HQ

Sedation and Analgesia Success Rate Adverse Effects Rate

Ma Lin [15]

2012

China

46

26–84 (months)

Midazolam

The cohort study

HQ

Sedation and Analgesia Success Rate Adverse Effects Rate

Nie Juan [16]

2021

China

45

3–12 (years)

Midazolam

Randomized controlled trial

HQ

Sedation and Analgesia Success Rate Adverse Effects Rate

Liu Jing [17]

2020

China

57

6–8 (years)

Nitrous Oxide

Randomized controlled trial

HQ

Sedation and Analgesia Success Rate Adverse Effects Rate

  1. HQ High Quality