Skip to main content

Table 1 Patient characteristics

From: Trehalose versus carboxymethylcellulose oral spray for relieving radiation-induced xerostomia in head and neck cancer patients: a randomized controlled trial

Participant characteristics

Intervention

CMC (n = 35)

Trehalose (n = 35)

Age

  

mean (years) ± SD

54.14 ± 13.89

58.29 ± 14.75

Range

36–75

22–85

Gender, n (%)

  

Male

23 (65.71%)

22 (62.86%)

Female

12 (34.29%)

13 (37.14%)

Primary cancer site, n (%)

  

Nasopharynx

25 (71.42%)

11 (31.43%)

Oral cavity

7 (20%)

12 (34.29%)

Salivary gland

1 (2.86%)

3 (8.57%)

Nasal cavity and paranasal sinus

1 (2.86%)

4 (11.43%)

Larynx

1 (2.86%)

4 (11.43%)

Thyroid

0 (0%)

1 (2.86%)

Stage of cancer, n (%)

  

Stage I

1 (2.86%)

1 (2.86%)

Stage II

3 (8.57%)

7 (20%)

Stage III

17 (48.57%)

13 (37.14%)

Stage IV

14 (40%)

14 (40%)

Radiation technique, n (%)

  

IMRT/VMATa

33 (94.29%)

32 (91.43%)

3D CRTb

2 (5.71%)

3 (8.57%)

Duration after radiation (months)

  

Mean ± SD

7.06 ± 3.86c

4.71 ± 3.41

Range

1–12

1–11

Concomitant chemotherapy, n (%)

32 (91.42%)d

23 (65.71%)

  1. a Intensity Modulated Radiation Therapy/Volumetric Modulated Radiation Therapy
  2. b Three-dimensional conformal radiation therapy
  3. c The mean duration after radiation of CMC was significantly higher than trehalose; Independent T test; p < 0.05
  4. d The percentage of patients receiving concomitant chemotherapy during CMC treatment was significantly higher than during trehalose treatment; Chi-square test; p < 0.05