Table 4 The median XeQoLs scores taken before and after treatment with CMC or trehalose solution spray
Questionnaire | XeQoLs score (Median ± IQR) | |||||
|---|---|---|---|---|---|---|
CMC group (n = 35) | Trehalose group (n = 35) | |||||
Before | After | ρ-value | Before | After | ρ-value | |
Part 1: Physical | ||||||
Q1: Rate your difficulty in chewing due to dryness | 4.00 ± 7.00 | 3.00 ± 5.00 | 0.002** | 0.00 ± 5.00 | 0.00 ± 4.00 | 0.015* |
Q2: Rate your difficulty in swallowing food due to dryness | 5.00 ± 4.00 | 3.00 ± 4.00 | 0.000*** | 5.00 ± 5.00 | 4.00 ± 4.00 | 0.000*** |
Q3: Rate your difficulty in talking due to dryness | 3.00 ± 5.00 | 2.00 ± 4.00 | 0.003** | 4.00 ± 5.00 | 3.00 ± 4.00 | 0.002** |
Q4: Rate your taste alteration | 5.00 ± 4.00 | 5.00 ± 4.00 | 0.000*** | 6.00 ± 4.00 | 5.00 ± 3.00 | 0.000*** |
Part 2: Pain / Discomfort | ||||||
Q5: Rate your feeling dry mouth | 6.00 ± 3.00 | 4.00 ± 3.00 | 0.000*** | 6.00 ± 3.00 | 4.00 ± 2.00 | 0.000*** |
Q6: Rate the frequency of sipping water (nocturnal) | 4.00 ± 5.00 | 3.00 ± 5.00 | 0.047* | 4.00 ± 5.00 | 3.00 ± 3.00 | 0.003** |
Q7: Rate the frequency of sipping water (daytime) | 8.00 ± 2.00 | 6.00 ± 4.00 | 0.001** | 0.00 ± 1.00 | 0.00 ± 1.00 | 0.000*** |
Q8: Rate your pain and discomfort | 0.00 ± 2.00 | 0.00 ± 2.00 | 0.768 | 0.00 ± 1.00 | 0.00 ± 1.00 | 0.066 |
Part 3: Psychological | ||||||
Q9: My mouth/throat dryness interferes with my daily activity | 2.00 ± 5.00 | 0.00 ± 4.00 | 0.011* | 0.00 ± 5.00 | 0.00 ± 4.00 | 0.005** |
Q10: My mouth/throat dryness makes me nervous | 2.00 ± 5.00 | 0.00 ± 5.00 | 0.006** | 0.00 ± 3.00 | 0.00 ± 3.00 | 0.004** |
Q11: My mouth/throat dryness reduces my general happiness | 0.00 ± 5.00 | 0.00 ± 4.00 | 0.019* | 0.00 ± 0.00 | 0.00 ± 4.00 | 0.046* |
Part 4: Social | ||||||
Q12: My mouth/throat dryness makes me uncomfortable speaking in front of other people | 0.00 ± 2.00 | 0.00 ± 2.00 | 0.103 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.180 |
Q13: My mouth/throat dryness makes me uncomfortable when eating in front of other people | 0.00 ± 4.00 | 0.00 ± 4.00 | 0.169 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.157 |
Q14: My mouth/throat dryness makes me from socializing (going out) | 0.00 ± 2.00 | 0.00 ± 2.00 | 0.211 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.109 |