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Table 4 Mean scores of clinical parameters and their Δ for PD ≥ 6 mm at baseline and 3 and 6 months in the test (SRP plus fish oil) and control (SRP alone) groups. Data are mean ± SD

From: Clinical and microbiological outcomes of subgingival instrumentation supplemented with high-dose omega-3 polyunsaturated fatty acids in periodontal treatment – a randomized clinical trial

Variables

Test group n = 20

Control group n = 20

Inter-group comparisons p value

No PD ≥ 6 mm

 Baseline

17.3 ± 17.1

15.6 ± 14.2

0.37

 3 months

12.2 ± 11.3*

12.6 ± 11.5*

0.46

 Δ baseline–3 months

5.05.7 ± 11.0

3.00 ± 3.5

0.22

 6 months

11.2 ± 10.9*#

11.4 ± 11.2*#

0.48

 Δ baseline–6 months

6.05 ± 12.7#

3.17 ± 2.5#

0.18

PD (mm)

 Baseline

6.42 ± 0.31

6.62 ± 0.39

0.05

 3 months

4.35 ± 0.98*

5.04 ± 0.71*

0.01

 Δ baseline–3 months

2.07 ± 0.96

1.58 ± 0.71

0.04

 6 months

4.17 ± 0.96*

4.47 ± 0.86*#

0.16

 Δ baseline– 6 months

2.25 ± 0.86

2.15 ± 0.78#

0.36

REC (mm)

 Baseline

0.83 ± 0.81

1.11 ± 1.06

0.18

 3 months

0.89 ± 0.94

1.50 ± 0.91*

0.03

 Δ baseline–3 months

0.15 ± 0.55

0.39 ± 0.84

0.16

 6 months

0.96 ± 1.18

1.59 ± 0.78*

0.03

 Δ baseline–6 months

0.22 ± 0.73

0.48 ± 0.85

0.17

CAL (mm)

 Baseline

7.25 ± 0.93

7.74 ± 1.09

0.08

 3 months

5.37 ± 1.30*

6.54 ± 1.17*

0.003

 Δ baseline–3 months

1.88 ± 0.96

1.19 ± 1.01

0.02

 6 months

5.26 ± 1.42*

6.06 ± 0.91*#

0.02

 Δ baseline–6 months

1.99 ± 0.88

1.68 ± 0.94#

0.15

BOP (%)

 Baseline

58.4 ± 26.6

63.2 ± 22.5

0.28

 3 months

35.0 ± 17.6*

44.1 ± 16.9*

0.05

 Δ baseline–3 months

23.4 ± 25.5

19.1 ± 32.2

0.33

 6 months

26.2 ± 19.9*

35.3 ± 18.1*

0.06

 Δ baseline–6 months

32.3 ± 30.2

27.4 ± 28.3

0.31

Closed pockets (%) with PD ≤ 4 mm and no BOP

 Baseline

0

0

-

 3 months

37.5 ± 25.5

26.4 ± 12.4

0.05

 6 months

50.2 ± 24.1#

38.3 ± 22.6#

0.05

  1. Abbreviations: PD probing depth, REC gingival recession, CAL clinical attachment level, BOP bleeding on probing
  2. Intra-group comparison: * p ≤ 0.05 compared to baseline; # p ≤ 0.05 compared to 3 months