Skip to main content
Fig. 6 | BMC Oral Health

Fig. 6

From: KAT2A-mediated succinylation modification of notch1 promotes the proliferation and differentiation of dental pulp stem cells by activating notch pathway

Fig. 6

Inhibition of Notch1 reversed the effects of KAT2A overexpression. (A) PCR analysis was performed to evaluate the mRNA levels of Notch1 in DPSCs after transfection. (B) Flow cytometry detected the DPSC cell cycle phase distribution after transfection. C–D. Alkaline phosphatase (ALP) straining of DPSCs after seven days of osteogenic induction. E–F. Calcium mineralization formation was observed by alizarin red staining at day 14 in DPSCs. G. Protein expression of osteogenic markers COL1a1 and RUNX2 analyzed by western blotting. **p < 0.01, ***p < 0.001 (vs. oe-NC or sh-NC group); ##p < 0.01 (vs. oe-KAT2A + sh-NC group)

Back to article page

BMC Oral Health

ISSN: 1472-6831

Contact us