Table 2 Statistical parameters of the total GI, PI and aMMP8 levels (ng/ml) at different time points

T0

GI

0.03

0.34 (0.39)

0.22

0.48

0 – 1.73

NA

NA

(n = 55)

PI

1.57

2.03 (0.68)

2.09

2.40

0 – 4

NA

NA

aMMP8

1.00

5.29 (7.08)

1.50

9.00

0 – 27

NA

NA

T1

GI

0.03

0.32 (0.40)

0.15

0.50

0 – 1.73

-0.01 (0.19)

0.6718

(n = 53)

PI

1.57

2.29 (0.92)

2.35

2.96

0 – 5

0.27 (0.86)

0.0279*

aMMP8

1.00

10.21 (9.95)

6.00

18.00

0 – 33

4.16 (9.15)

0.0017*

T2

GI

0.03

0.48 (0.48)

0.39

0.73

0 – 1.81

0.14 (0.36)

0.0063*

(n = 55)

PI

1.75

2.38 (0.87)

2.25

3.12

1 – 4

0.35 (0.89)

0.0055*

aMMP8

1.00

8.55 (9.54)

5.50

11.00

0 – 39

2.63 (10.45)

0.0677

T3

GI

0.25

0.68 (0.53)

0.55

1.00

0 – 2.09

0.34 (0.45)

0.0001^**

(n = 55)

PI

1.93

2.48 (0.82)

2.48

3.11

1 – 4

0.44 (0.80)

0.0002*

aMMP8

1.00

12.26 (12.8)

9.50

20.00

0 – 53

6.34 (11.87)

0.0002*

T4

GI

0.30

0.72 (0.54)

0.57

1.08

0 – 1.98

0.38 (0.49)

0.0001^**

(n = 54)

PI

1.58

2.23 (0.80)

2.08

3.00

1 – 4

0.20 (0.75)

0.0533

aMMP8

1.00

10.43 (11.7)

5.50

18.00

0 – 48

4.42 (13.43)

0.0192*

T5

GI

0.45

0.95 (0.60)

0.85

1.45

0 – 2.33

0.62 (0.62)

0.0001^**

(n = 50)

PI

1.69

2.39 (0.83)

2.39

3.03

1 – 4

0.35 (0.96)

0.0126*

aMMP8

1.00

13.05 (11.9)

11.0

20.00

0 – 43

7.01 (12.04)

0.0001*