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Table 2 Findings of clinical and radiographic studies on diode laser in vital pulp therapy

From: The application of lasers in vital pulp therapy: clinical and radiographic outcomes

Author

Study type

Number of teeth

Treatment type

Materials used in vital pulp therapy

Laser characteristics

Follow-up duration

Results

Yadav et al

[34]

Human in vivo

45 primary molar teeth

Pulpotomy

FS + ZOE + GI

Electrosurgery + ZOE + GI

Laser + ZOE + GI

Diode

810-nm

3 W

CW

2–3 s

Contact Mode

1,3,6,9 months

The overall clinical success rate: (non-sig)

FS:86.6%

ES:100%

Laser:100%

The overall radiographic success rate: (non sig)

FS:80%

ES:80%

Laser:80%

Most common radiographic findings of failure: Internal resorption

Yazdanfar et al

[12]

Human in vivo

10 permanent teeth

10 permanent Ant&Post. teeth

Pulp capping

RMGI + Composite

Laser + RMGI + 

composite

Diode Laser

(Hemostasis)

808- nm

CW

1.5 W

Contact Mode

 + 

(Decontamination)

808-nm

CW

1 W

Contact Mode

1,6,12 months

Clinical success rate after 1 year: (sig)

RMGI:60%

Laser:100%

The failed treatments were related to youngest patients which reflects the importance of microbial free environment than age

Durmus et al. [29]

Human in vivo

120 primary molar teeth

pulpotomy

FC + ZOE + GI + 

SS crown

FS + ZOE + GI + 

SS crown

Diode laser + 

ZOE + GI + 

SS crown

Diode laser

810-nm

1.5 W

30 Hz

50 mJ

10 s

Non contact (1-2 mm) mode/air cooling (without water)

1,3,6,9,12 months

Clinical success rate after1,3,6,9,12 months as follows: (not sig.)

FC:100%-100%-100%-97.5%-97.5%

FS:100%-100%-97.5%-95%-92.5%

Laser:100%-100%-100%-100%-100%

Radiographic success rate for 1,3,6,9,12:(non sig.) FC:100%-97.5%-92.5%-90%-87.5%

FS:100%-95%-87.5%-84.6%-79.5%

Laser:100%-95%-87.5%-87.5%-75%

Gupta et al. [54]

Human in vivo

30 primary molars

pulpotomy

FS

Electrosurgery

Laser

Diode laser

980 nm

3W

Continuous pulse mode

Contact mode

4 J/cm2

31 s

3,6,9,12 months

Clinical & radiographic success rate after3,6,9,12 months: (sig.)

FS:80%-80%-80%-80%

ES:80%-80%-80%-80%

Laser:100%-100%-100%-100%

Joshi et al. [31]

Human in vivo

40 primary teeth

pulpotomy

Diode laser + ZOE + GI

FC + ZOE + GI

Diode laser

980-nm

Continuous mode

2 s

Contact mode

1.5 W

3,6,12

months

Clinical success rate after3,6,12 months: (non sig.)

Diode laser:100%,100%,100%

FC:100%,100%,100%,100%

Radiographic success rate after3,6,12 months: (non sig.)

Diode laser:100%,94.4%,78.8%

FC:94.4%,78.8%,57.8%

Niranjani et al. [26]

Human in vivo

60 primary molars

pulpotomy

MTA + ZOE + SS crown

Laser + ZOE + SS crown

BD + ZOE + 

SS crown

Diode laser

810 nm

Contact mode

1.5W

2 s

3,6

Months

Clinical and radiographic success rate after 6 monthes in MTA group was 100%. (non sig.)

Pratima et al. [30]

Human in vivo

40 primary molars

pulpotomy

Laser + MTA + ZOE + SS crown

Laser + ZOE + SS crown

Diode laser

980-nm

2.5–3 W

Contact mode

3,6,12 months(clinically)

6,12 months(radiographically)

Clinical success rate after 3,6,12 months: (non sig.)

Laser + MTA:100%,100%,100%

Laser + ZOE:94%,94%,94%

Radiographic success rate after 6,12monthes:(non sig.)

Laser + MTA:100%,100%

Laser + ZOE:94%,94%

Saltzman et al. [27]

Human in vivo

52 primary teeth

pulpotomy

Laser + MTA + GIC + SS crown

FC + ZOE + SS crown

Diode laser

980-nm

3 W

Continuous mode

Contact mode

2.3,5.2,9.5,15.7 months

Radiographic success rate after 2.3,5.2,9.5,15.7 months: (non sig)

Laser + MTA:95.8%,94.7%,77.8%,71.4% (overal:70.84%)

FC + ZOE:100%,100%,94.7%,84.6%,(overall:87.5)

All teeth in both treatment groups were regarded as clinically successful at each follow up period

Clinical-pathological evaluation showed that apart from expected histologic changes, iatrogenic errors were present in all teeth that were considered as failure

Yazdanfar et al. [43]

Human in vivo

20 permanent teeth

Pulp Cap

TheraCal (Resin Modified Calcium Silicate Paste) + Scotchbond + Composite

Laser + TheraCal + Scotchbond + Composite

Diode Laser

808-nm

1.5W

CW

Contact Mode

190.98 W/cm2

381.97 J/cm2

1,3,6 months

Clinical assessment:

All The teeth in both groups remained vital after 6 monthes

All the teeth in TheraCal group showed slight sensitivity to cold test. (Significantly more than Laser group)

Radiographic assessment:

There was not significant difference among groups

The Laser group showed higher thickness and better integrity in regard to reparative dentin formation

Pei et al. [33]

Human in vivo

90 primary molar teeth

pulpotomy

FC + IRM + SS crown

Laser + IRM + SS crown

Diode laser

915-nm

2 W

100 Hz

Contact mode

1 s (3times)

3,6,12

months

Clinical success rate after 3,6,12 months: (non sig.)

Laser:100%,96.8%,92.9%

FC:100%,97.1%,90.9%

Radiographic success rate after 3,6,12 months:(non sig.)

Laser:100%,90.3%,78.6%

FC:100%,91.4%,72.7%

Swarnalatha et al. [55]

Human in vivo

40 primary teeth

pulpotomy

MTA + GIC + SS crown

Laser + MTA + GIC + SS crown

Diode laser

810-nm

Continuous mode

Contact mode

1.5 W

2 s

3,6,9

months

Clinical success rate after3,6,9monthes:

MTA:90%,84.21%,88.23%

Laser:95%,94.74%,99.44%

Radiographic success rate after 3,6,9monthes:

MTA:85%,84.21%,82.3%

Laser:90%,89.47%,88.89%

Kuo et al

[25]

Human in vivo

145 primary molars

pulpotomy

Laser (hemostasis) + 

ZOE + GI + SS crown/Composite resin

NaOCl (hemostasis) + 

ZOE + GI + SS crown/composite resin

Sterelized dry cotton pellet (hemostasis) + 

ZOE GI + SS crown/Composite resin

Diode Laser

970-nm

3 W

5 Hz

Water cooling

6,12,18,24 months

Clinical success rate after 6,12,18,24 months:

Laser:100%,100%,100%,100%

NaOCl:98.8%,96.2%,94.4%,88.9%

No medication:100%,100%,100%,100%

(Sig. difference between Laser&NaOCl after 24 months)

Radiographic success rate after after 6,12,18,24 months:

Laser:100%,97.6%,97.4%,90.9%

NaOCl:98.8%,85.7%,82.2%,65.7%

No medication:100%,92.6%,92.6%,87.5%

(Sig. difference between Laser&NaOCl after 12,18,24 months)

Sharma et al. [41]

Human in vivo

40 permanent molar teeth

Indirect pulp cap

RMGI + IRM

Laser + RMGI + 

IRM

BD + IRM

Laser + BD + IRM

Diode Laser

980-nm

1 W

CW

Contact mode

10 s

3,6,12 months

Clinical assessment:

All the teeth were vital and had positive response in regard to cold test and Electrical Pulp Test

Radiographic assessment:

The thickness of dentin deposited after 12 months: (non sig)

RMGI:0.07 mm

Lser + RMGI:0.10 mm

BD:0.25 mm

Laser + BD:0.32 mm

Aripirala et al. [40]

Human in vivo

100 Primary molar teeth

pulpotomy

Diode laser + RMGI + 

SS Crown

SV(Simvastatine gel) + RMGI + SS Crown

Diode laser

940-nm

2 W

4 J/cm2

70–80 Hz

Gated pulse mode (for pulp amputation)

CW (for hemostasis)

3,12 months

Clinical & radiographic success rate after 12 months:(non- sig)

Laser:76.1%,52.1%

SV:80.4%,65.2%

Satyarth

[28]

Human in vivo

40 primary teeth

pulpotomy

MTA

Laser + MTA

Diode Laser

810 nm

CW

1.5W

Contact mode

3,6,9 months

Clinical success rate after 3,6,9 months:

MTA:90%,84.21%,88.23%

Laser:95%,94.74%,94.44%

Radiographic success rate after 3,6,9 months:

MTA:85%,84.21%,82.3%

Laser:90%,89.47%,88.89%

Shaikh et al. [38]

Human in vivo

40 primary teeth

pulpotomy

FC

Laser

Diode Laser

810-nm

1.5 W

Continuous Mode

Contact Mode

10 s

1,3,6,9 months

There was no significant clinical and radiographic difference between the two groups

Ansari et al.[24]

Human in vivo

40 primary teeth

pulpotomy

Laser + Reinforced ZOE + SS Crown

FC + Reinforced ZOE + SS Crown

Diode Laser

810-nm

Non-contact

10 W

20 Hz

6,12 months

Clinical success rate after 6,12 months: (non sig)

FC:100%,100%

Laser:100%,100%

Radiographic success rate after 6,12 months: (non sig)

FC:100%,100%

Laser:95%,90%