Fig. 2

Morphology of hPDLFs under pressure. After 24 h of pressure, the fibroblasts appeared flattened and expanded and showed many extensions (stolons) in the electron micrographs. A Control hPDLFs (bar = 100 µm), B HPDLFs under pressure (bar = 100 µm, 50 µm, stolons marked by white arrows), C HPDLFs treated with MTX (1 µg/ml) (bar = 100 µm), D HPDLFs treated with MTX (1 µg/ml) and pressure (bar = 100 µm, 50 µm, stolons marked by white arrows)