Inflammatory cytokines mediating the effect of oral lichen planus on oral cavity cancer risk: a univariable and multivariable mendelian randomization study

Table 1 UVMR analysis of the causal effects of OL and OLP on OCC.

Outcome: OCC	OR	95%CI	P-value
Exposure: OL
IVW	1.229	0.832–1.814	0.300
Weighted median	1.072	0.754–1.525	0.697
MR-Egger regression	0.749	0.303–1.850	0.548
Exposure: OLP
IVW	1.417	1.167–1.721	0.001<
Weighted median	1.380	1.067–1.785	0.014
MR-Egger regression	1.158	0.780–1.719	0.484

Abbreviations: UVMR = univariable Mendelian randomization; IVW = inverse variance weighted; OCC = oral cavity cancer; OL = oral leukoplakia; OLP = oral lichen planus; CI = confidence interval; OR = odds ratio;

ISSN: 1472-6831