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Table 3 Heterogeneity and pleiotropy analysis

From: Inflammatory cytokines mediating the effect of oral lichen planus on oral cavity cancer risk: a univariable and multivariable mendelian randomization study

Exposure

Outcome

nSNP

Heterogeneity

MR-Egger

MR-PRESSO

Method

Cochran’s Q

P-value

Egger-intercept

P-value

P-value

OLP

OCC

12

IVW

10.522

0.484

0.045

0.277

0.515

OLP

IL-13

11

IVW

8.109

0.618

0.012

0.481

0.639

OLP

IL-9

11

IVW

9.748

0.463

0.022

0.196

0.450

IL-13

OCC

8

IVW

8.863

0.263

0.104

0.085

0.399

  1. Abbreviations: IVW = inverse variance weighted; OLP = oral lichen planus; OCC = oral cavity cancer; IL-13 = interleukin-13; IL-9 = interleukin-9; SNP = single-nucleotide polymorphism;