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Table 1 Distribution and types of p16INK4A and HSV expression in relation with the subjects age and gender

From: HPV related p16INK4A and HSV in benign and potentially malignant oral mucosa pathologies

Investigated specimens

Study group

Total = 211

Median age

(years) (25Q ÷ 75Q)

P

age

Female

Total = 147

Male

Total = 64

P

gender

p16INK4A expression intensity

Int 1 – 23 P (39%)

53.0 (46.0 ÷ 59.0)

p = 0.0024

16 (10.9%)

7 (10.9%)

p = 0.700

χ22 = 0.71

Int 2 – 25 P (42.4%)

61,0 (48.0 ÷ 68.0)

65,0 (62.0 ÷ 71.0)

20 (13.6%)

5 (7.8%)

Int 3 – 11 P (18.6%)

8 (5.4%)

3 (4.7%)

HSV expression intensity

Int 1—19 (90.5%)

53

60

 

14 (9.5%)

2

5 (7.8%)

0.0

p = 0.999

Int 2—2 (9.5%)

Int 3—0 specimens