Table 4 Pattern and intensity of p16INK4A and HSV expression in connection with most significant clinical diagnosis
From: HPV related p16INK4A and HSV in benign and potentially malignant oral mucosa pathologies
Clinical diagnosis | p16INK4A distribution pattern number of specimens | p16INK4A expression intensity number of specimens | HSV distribution pattern number of specimens | HSV expression intensity number of specimens | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lack of p16INK4A expression | Focal | Diffuse | Int 1 | Int 2 | Int 3 | Lack of p16INK4A expression | Focal | Diffuse | Int 1 | Int 2 | Int 3 | |
Oral lichen planus N = 30 | 12 40.0% | 9 30.0% | 9 30.0% | 3 10.0% | 9 30.0% | 6 20.0% | 29 96.7% | 1 3.3% | 0 0.0% | 1 3.3% | 0 0.0% | 0 0.0% |
Leukoplakia N = 13 | 6 46.1 | 3 23.1% | 4 30.8% | 2 15.4% | 3 23,1% | 2 15.4% | 11 84.6% | 1 7.7% | 1 7.7% | 2 10.5% | 0 0.0% | 0 0.0% |
Overgrowth of mucosa N = 135 | 106 78.5% | 21 15.6% | 8 5.9% | 15 11.1% | 11 8.1% | 3 2.22% | 120 88.9% | 9 6.7% | 6 4.4% | 14 10.4% | 1 1.0% | 0 0.0% |