Skip to main content
Fig. 7 | BMC Oral Health

Fig. 7

From: Inhibition of ZDHHC16 promoted osteogenic differentiation and reduced ferroptosis of dental pulp stem cells by CREB

Fig. 7

CREB regulated the effects of ZDHHC16 on Ferroptosis of DPSCs

CREB agonist promoted GSH activity levels (A), reduced iron concentration (B) and LDH activity levels (C), inhibited PI-positive cells (D), increased MPT (E) and JC-1 disaggregation (F) of DPSCs by ZDHHC16 up-regulation; CREB inhibitor reduced GSH activity levels (G), increased iron concentration (H) and LDH activity level (I), promoted PI-positive cells (J), and suppressed MPT (K) and JC-1 disaggregation (L) of DPSC by ZDHHC16 down-regulation.

**p < 0.01 compared with negative or si-nc, ##p < 0.01 compared with ZDHHC16 or si-ZDHHC16.

Back to article page

BMC Oral Health

ISSN: 1472-6831

Contact us