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Fig. 3 | BMC Oral Health

Fig. 3

From: Artesunate-loaded thermosensitive chitosan hydrogel promotes osteogenesis of maxillary tooth extraction through regulating T lymphocytes in type 2 diabetic rats

Fig. 3

ART-loaded TCH alleviated maxilla bone loss on tooth extraction sockets of T2DM. A, B Representative images of the maxilla by micro-CT at day 0 (A) and day 60 (B) after tooth extraction in each group. C–E The loss of maxilla bone height of buccal (C), middle (D), and palatal (E) after tooth extraction in T2DM rats (n ≧ 3). F Bone mineral density of the maxilla after extracting the tooth in T2DM rats (n ≧ 3). Compared with the T2DM group, the 150 mg/ml ART-loaded TCH group significantly alleviated maxilla bone height and Bone mineral density (p < 0.01). *p < 0.05 and **p < 0.01. T2DM, type 2 diabetes mellitus group; TCH, thermosensitive chitosan hydrogel group; Low, 50 mg/ml ART-loaded TCH group; Medium, 100 mg/ml ART-loaded TCH group; High; 150 mg/ml ART-loaded TCH group

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BMC Oral Health

ISSN: 1472-6831

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