Fig. 4

The relative abundance of genus for saliva (Fig. 4-a,b) and dental plaque (Fig. 4-c,d) samples in RC, DC and HP groups. In the level of Genus, top 10 are Prevotella, Veillonella, Streptococcus, Actinomyces, Fusobacterium, Capnocytophaga, Selenomonas, Leptotrichia, Campylobacter. In saliva samples, Veillonella and Streptococcus of group RC is higher than DC and HP. Neisseria and Haemophilus are significant reduced. The overall expression of Prevotella expressed high both in saliva and plaque. It is increased significantly for RC group in saliva, but there was no significant difference in plaque among the three groups. (* P < 0.05, ** P < 0.01, *** P < 0.01)