Periodontal disease-associated micro-organisms in peri-menopausal and post-menopausal women using or not using hormone replacement therapy. A two-year follow-up study

Table 2 Odds ratios (OR) with 95% confidence intervals (95% CI) of the statistically significant explanatory factors after backward elimination for the prevalence of periodontal micro-organisms analyzed by stepwise logistic regression.

Bacterium#	Explanatory factor§	OR	95% CI	Significance
Baseline
P.g.	Periodontal pockets	3.73	1.74-8.00	p = 0.001
P.i.	Periodontal pockets	2.77	1.57-4.91	p < 0.001
P.n.	Poor oral health	0.40	0.19-0.82	p = 0.012
T.f.	Periodontal pockets	4.44	2.44-8.07	p < 0.001
T.d.	Periodontal pockets	2.26	1.28-3.97	p = 0.005
2 year-Follow-up
A.a.	HRT§§	0.21	0.48-0.93	p = 0.040
	Cardiovascular
	medication§§§	5.48	1.04-28.77	p = 0.044
P.g.	Periodontal pockets	3.04	1.11-8.34	p = 0.031
P.i.	Periodontal pockets	1.98	1.09-3.59	p = 0.025
P.n.	Number of teeth	1.08	1.00-1.16	p = 0.045
T.d.	Periodontal pockets	2.95	1.06-8.19	p = 0.038

#A.a. = Aggregatibacter actinomycetemcomitans; P.g. = Porphyromonas gingivalis;
P.i. = Prevotella intermedia; P.n. = Prevotella nigrescens; T.f. = Tannerella forsythia; T.d. = Treponema denticola.
§Periodontal pockets: >4 mm deep pockets; Poor oral health = self-assessed poor oral health;
§§HRT = hormone replacement therapy
§§§Includes diuretics, antihypertensive agents, nitrates, digitalis and antiarrhythmic agents

ISSN: 1472-6831