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Table 4 Predisposing factors for bloodstream infection in febrile episodes of neutropenic and non- neutropenic patients in radiotherapy, chemotherapy and radio chemotherapy treated cases

From: Incidence and risk factors for infection in oral cancer patients undergoing different treatments protocols

Causative factors

Group = 1

Group = II

Group = III

ANC

ANC

ANC

<500 ≥500

<500 ≥500

<500 ≥500

Duration of neutropenia >7

5(7.81) 4(4.70)

6(6.6) 4(7.27)

10(8.92) 6(6.31)

P = 0.49

P = 1

P = 0.65

Oral mucositis (grade 0)

5(7.81) 3(3.52)

5(5.55) 4(7.27)

5(4.46) 2(1.78)

P = 0.28

P = .73

P = .45

Oral mucositis (grade 1)

6(9.37) 3(3.52)

2(2.22) 5(9.09)

7(6.25) 6(6.31)

P = 0.17

P = 0.10

P = .78

Oral mucositis (grade 2)

4(6.25) 5(5.88)

4(4.44) 5(9.09)

12(10.71) 4 (4.21)

P = 1

P = 0.30

P = .13

Oral mucositis (grade 3)

5(7.81) 8(9.41)

9(10) 6(10.90)

15(13.39) 7(7.36)

P = 0.78

P = 0.91

P = .23

Oral mucositis (grade 4)

7(10.93) 25(29.41)

11(12.22) 12(21.81)

32(28.57) 12(12.63)

P < .01**

P =0.19

P < .001***

Anemia

4(6.25) 3(3.52)

10(11.11) 3(5.45)

9(8.03) 6(6.31)

P = .46

P = .37

P = .83

Central venous line present

8(12.5) 7(8.23)

15(16.6) 5(9.09)

7(6.25) 15(15.78)

P = .56

P = .30

P = .05*

Peripheral line present

5(7.81) 3(3.52)

9(10) 5(9.09)

4(3.57) 10(10.52)

P = .02

P = 91

P = .08

Community acquired

6(9.37) 20(23.52)

6(6.06) 2(3.63)

6(5.35) 11(11.57)

P < .05*

P = .71

P = .17

Nosocomial acquired

9(14.06) 4(4.70)

13(14.44) 4(7.27)

5(4.46) 16(16.84)

 

P = .08

P = .29

P < .001***

  1. Note: % had been shown in parenthesis, the value in table shows number of patients, ANC = absolute neutrophil count, ANC of <500 neutrophil/micro L (neutropenic), ANC ≥500 neutrophil/micro L (non-neutropenic). P = Probability value with an ANC of <500 neutrophil/micro L (neutropenic) vs. those with ANC >500 neutrophil/micro L (non-neutropenic). P < .05 * less significant, P < .01 ** significant, P < .001 *** highly Significant.