Figure 5
Association of the DEFB1 -44 SNP genotype with increased constitutive antimicrobial activity. Total cell lysates prepared from cultured keratinocytes (4 μg protein) were added to solidified agarose containing S. epidermidis. The area of clearing in square mm. minus the area of the well was calculated and results compared by genotype. The data represent 3 replicates from each cell line and the assay was performed in duplicate. The data are log transformed and the mean and std. dev. are shown.