Table 1 The functional analysis of the DEGs

BP

GO:0001775

cell activation

68

<1.00E-16

BP

GO:0002253

activation of immune response

48

<1.00E-16

BP

GO:0002376

immune system process

165

<1.00E-16

BP

GO:0002682

regulation of immune system process

94

<1.00E-16

BP

GO:0002684

positive regulation of immune system process

73

<1.00E-16

CC

GO:0005576

extracellular region

138

<1.00E-16

CC

GO:0005615

extracellular space

70

<1.00E-16

CC

GO:0044421

extracellular region part

86

<1.00E-16

CC

GO:0071944

cell periphery

191

2.64E-14

CC

GO:0005886

plasma membrane

186

1.49E-13

MF

GO:0008009

chemokine activity

10

2.35E-07

MF

GO:0003823

antigen binding

12

4.64E-07

MF

GO:0032403

protein complex binding

26

4.85E-07

MF

GO:0042379

chemokine receptor binding

10

1.11E-06

MF

GO:0005178

integrin binding

12

1.41E-06

BP

GO:0043588

skin development

311

2.33E-14

BP

GO:0008544

epidermis development

280

1.18E-12

BP

GO:0030216

keratinocyte differentiation

108

1.09E-09

BP

GO:0009913

epidermal cell differentiation

154

1.01E-08

BP

GO:0009888

tissue development

1479

2.09E-08

CC

GO:0030057

desmosome

22

5.73E-06

CC

GO:0005882

intermediate filament

191

2.33E-05

CC

GO:0045111

intermediate filament cytoskeleton

231

2.76E-05

CC

GO:0045095

keratin filament

93

0.00096928

CC

GO:0005911

cell-cell junction

297

0.00108577

MF

GO:0005198

structural molecule activity

627

2.89E-05

MF

GO:0005200

structural constituent of cytoskeleton

94

0.00104197

MF

GO:0016755

transferase activity, transferring amino-acyl groups

24

0.003031659

MF

GO:0016702

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

25

0.003414279

MF

GO:0016701

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen

26

0.003825148