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Table 3 Summary of treatment differences in MLSI regions by week (ITT population n = 154)

From: A randomised clinical trial to evaluate the effect of a 67 % sodium bicarbonate-containing dentifrice on 0.2 % chlorhexidine digluconate mouthwash tooth staining

Region

Week

Difference (95 % CI)b

% Diffb

P-value

Overall MLSI

3

−0.09 (−0.24, 0.06)

−22.6

0.1552

6a

−0.20 (−0.51, 0.10)

−19.9

0.1313

Overall Facial MLSI

3

−0.09 (−0.20, 0.01)

−39.2

0.0529

6

−0.23 (−0.49, 0.02)

−32.2

0.0404

Overall Interproximal MLSI

3

−0.13 (−0.36, 0.09)

−22.0

0.1873

6

−0.28 (−0.74, 0.18)

−18.4

0.1713

Overall Gingival and Interproximal MLSI

3

−0.12 (−0.31, 0.07)

−22.8

0.1614

6

−0.23 (−0.60, 0.15)

−18.2

0.1709

  1. aPrimary objective; b Diff difference is 67 % NaHCO3 dentifrice minus control dentifrice. A negative difference favours the former. Results are based on back transformed data based on square root transformation; bold text indicates a statistically significant value