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Table 4 Summary of treatment differences by site (ITT population n = 154)

From: A randomised clinical trial to evaluate the effect of a 67 % sodium bicarbonate-containing dentifrice on 0.2 % chlorhexidine digluconate mouthwash tooth staining

Site

Week

Difference (95 % CI)

% Diffa

P-value

Overall MLSI

 1

3

−0.26 (−0.43, −0.09)

−52.1

0.0016

6

−0.44 (−0.77, −0.10)

−41.2

0.0072

 2

3

0.08 (−0.16, 0.31)

22.6

0.4621

6

0.05 (−0.44, 0.54)

5.5

0.8038

Facial overall MLSI

 1

3

−0.19 (−0.32, −0.06)

−64.8

0.0019

6

−0.40 (−0.68, −0.12)

−53.0

0.0032

 2

3

0.00 (−0.17, 0.17)

1.2

0.9757

6

−0.04 (−0.45, 0.36)

−6.4

0.8105

Overall interproximal MLSI

 1

3

−0.36 (−0.62, −0.10)

−49.7

0.0043

6

−0.61 (−1.12, −0.10)

−39.2

0.0126

 2

3

0.10 (−0.25, 0.45)

19.4

0.5421

6

0.09 (−0.65, 0.83)

6.0

0.7888

Overall gingival and interproximal MLSI

 1

3

−0.31 (−0.53, −0.09)

−51.0

0.0029

6

−0.50 (−0.91, −0.09)

−39.6

0.0108

 2

3

0.08 (−0.21, 0.38)

19.0

0.5409

6

0.09 (−0.52, 0.69)

6.9

0.7550

  1. aDiff = Difference is 67 % NaHCO3 dentifrice minus control dentifrice. A negative difference favours 67 % NaHCO3 dentifrice. Results based on back transformed data based on square root transformation; bold text indicates a statistically significant value.