Table 3 Characteristics of included studies

Borea (1993) [21]

T: continued OAT.

C: discontinued OAT.

T: 3–4.5

C: 1.5–2.5

T: Sutures and TA irrigation at surgery and MS for 7 day.

C: Sutures and physiologic irrigation at surgery and MS for 7 days.

Single dental

7 days

Day 1:

Spontaneous bleedings T: 1/15 C:2/15

Induced bleedings T:1/15 C:0/15

Day 2 to day 7: none

Evans (2002) [16]

T: continued OAT.

C: discontinued OAT 2 days before extractions and resumed on the same day.

T: 2.5(1.2–4.7)

C: 1.6(1.2–2.3)

All groups:

Oxycellulose dressing and sutures for all patients.

T: 2(1–7)

C: 3(1–9)

7 days

Postoperative bleeding

T:15/57 C:7/52

Devani (1998) [7]

T: continued OAT.

C: discontinued OAT 2 days before extractions.

T: 2.7(2.2–3.9)

C: 1.6(1.2–2.1)

All groups:

Placing haemostatic pack and sutures.

T: 2.1(1–9)

C: 2(1–9)

5 days

Minor bleeding:

Day 1 T:0/33 C:0/32 Day 2 T:0/33 C:1/32 Day 3 T:1/33 C:0/32 Day 4 to day 5:none

Gaspar (1997) [23]

T: continued OAT

C: discontinued OAT 3 days before and resumed the same day

T: 2.5(1.9–3.5)

C: 1.4(1.3–1.9)

All groups:

Sutures and TA irrigation at surgery and MS for 2 min.MS for 7 days postoperativedays

NR

7 days

Postoperative bleeding

T:2/32 C:1/15

Al-Mubarak (2007) [4]

T: continued OAT (group2 no sutures,group4 sutures).

C: discontinued OAT 2 days before and resumed 12 h after dental extractions (group1 no sutures, group 3 sutures).

T: 1.85(1.4–2.3)

C:2.55(1.9–3.1)

Local pressure (all) and sutures (group 3 and 4).

All patients range 1–5,

single extraction (63.3) two teeth (25 %), three teeth (7.5 %) four teeth (3.3 %) and five teeth (0.8 %).

7 days

Postoperative bleeding

T:8/110 C:7/114

Duan XQ (2010) [22]

T: continued OAT.

C: discontinued OAT 3 days before and resumed the next day.

ALL: 1.80–2.67

All groups:

Local pressure and sutures.

T:1.5(1–5)

C:1.3(1–5)

1 day

Postoperative bleeding

T:6/67 C:5/49