From: Salivary and serum inflammatory mediators among pre-conception women with periodontal disease
Inflammatory mediator | Women with overall periodontal disease versus without periodontal disease (mean ± SD) N = 533 | Women with moderate/severe periodontal disease versus without periodontal disease (mean ± SD) N = 338 | ||||
---|---|---|---|---|---|---|
Crude ratio | Adjusted ratioa | P | Crude ratio | Adjusted ratioa | P | |
Saliva | ||||||
IL-1β (pg/ml) | 1.23 | 1.23 | <0.001 | 1.26 | 1.25 | <0.001 |
β-glucuronidase (U/L) | 1.09 | 1.10 | <0.001 | 1.13 | 1.13 | <0.001 |
TNF-α (pg/ml) | 1.36 | 1.36 | <0.001 | 1.39 | 1.40 | <0.001 |
IL-6 (pg/ml) | 1.21 | 1.21 | <0.001 | 1.25 | 1.25 | <0.001 |
Serum | ||||||
IL-1β (pg/ml) | 1.49 | 1.49 | <0.001 | 1.48 | 1.50 | 0.001 |
β-glucuronidase (U/L) | 1.13 | 1.12 | 0.048 | 1.15 | 1.15 | 0.025 |
TNF-α (pg/ml) | 1.54 | 1.53 | <0.001 | 1.62 | 1.62 | <0.001 |
IL-6 (pg/ml) | 1.17 | 1.18 | 0.039 | 1.16 | 1.17 | 0.077 |