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Fig. 6 | BMC Oral Health

Fig. 6

From: PDGFRβ+/c-kit+ pulp cells are odontoblastic progenitors capable of producing dentin-like structure in vitro and in vivo

Fig. 6

BMP2 stimulated and PDGF-BB inhibited mineralization of PDGFRβ+/c-kit+ pulp cells. a Alizarin Red S staining. Dark red area indicates mineralization in the culture. Scale bar = 100 μm. b Quantitative Alizarin Red S analysis. PDGFRβ+/c-kit+ pulp cells produced significantly more mineralization when cultured in mineralization media than that of the nondifferentiation media. 1000 ng/ml BMP2 stimulated significantly more mineralization by PDGFRβ+/c-kit+ cells than in mineralization media alone. PDGF-BB suppressed mineralization in a concentration dependent manner when compared with mineralization media alone. * denotes p < 0.05 compared with undifferentiation media. ** denote p < 0.05 compared with mineralization media

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BMC Oral Health

ISSN: 1472-6831

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