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Table 1 Clinical parameters and bacterial levels at baseline in the patients with stable CP and progressive CP

From: Assessing the progression of chronic periodontitis using subgingival pathogen levels: a 24-month prospective multicenter cohort study

 

Stable CP patients (n = 62)

Progressive CP patients (n = 62)

p-value

Gender (male/female)

23/39

26/36

0.199

Age (year)

60.0 (56.0–66.0)

61 (52.5–68.0)

0.193

Smoking (non-smoker/smoker)

59/3

61/1

0.619

PlI

0.12 (0.06–0.30)

0.17 (0.07–0.45)

0.291

BOP (% positive)

3.62 (1.53–11.28)

6.54 (2.48–10.45)

0.022*

PPD (mm)

2.15 (1.80–2.53)

2.26 (1.76–2.57)

0.885

The deepest PPD (mm)

4.0 (4.00–6.00)

5.0 (4.25–7.75)

<0.001*

CAL (mm)

2.8 (2.34–3.33)

2.87 (2.78–3.62)

0.710

The deepest CAL (mm)

7.00 (5.25–8.00)

7.5 (6.25–9.00)

0.042*

P. gingivalis counts (log10) Subgingival plaque

1.00 (1.00–3.17)

1.64 (1.00–4.29)

<0.001*

P. gingivalis counts (log10) Saliva

2.59 (1.00–3.66)

3.34 (2.67–4.08)

0.002*

P. gingivalis IgG titers (EU)

1.28 (0.32–4.26)

1.63 (0.95–6.34)

0.503

P. intermedia counts (log10) Subgingival plaque

1.00 (1.00–1.63)

1.00 (1.00–2.72)

0.049*

P. intermedia counts (log10) Saliva

1.87 (1.00–3.65)

3.02 (1.41–4.05)

0.038*

P. intermedia IgG titers (EU)

−0.39 (0.47–0.13)

−0.27 (0.45–0.21)

0.173

A. actinomycetemcomitans counts (log10) Subgingival plaque

1.00 (1.00–1.00)

1.00 (1.00–1.00)

0.164

A. actinomycetemcomitans counts (log10) Saliva

1.00 (1.00–1.00)

1.00 (1.00–1.50)

0.065

A. actinomycetemcomitans IgG titers (EU)

−0.26 (0.41–0.03)

−0.30 (0.40–0.10)

0.278

  1. Value represent median value (25–75 percentile). CP chronic periodontitis, PlI plaque index, BOP bleeding on probing, PPD probing pocket depth, CAL clinical attachment level, EU enzyme-linked immunosorbent assay unit
  2. The deepest PPD and the deepest CAL indicate the value of the sites which is the deepest PPD and the deepest CAL in each subject, respectively. p values for gender were calculated using the Fisher’s exact test, and all others were Mann Whitneys’ U tests. The *mark represent statistical significance between stable CP patients and progressive CP patients (p < 0.05)