Assessing the progression of chronic periodontitis using subgingival pathogen levels: a 24-month prospective multicenter cohort study

Table 2 Diagnostic values of subgingival plaque bacterial levels and serum IgG titers for periodontal bacteria

	Cutoff	p-value	Sensitivity	Specificity	Positive predictive value	Negative predictive value	Likelihood ratio	AUC
P. gingivalis counts (log₁₀)	1.370	<0.001	0.548	0.774	0.708	0.632	2.429	0.666
P. intermedia counts (log₁₀)	1.040	0.077	0.371	0.774	0.622	0.552	1.643	0.568
A. actinomycetemcomitans counts (log₁₀)	1.151	0.171	0.065	0.984	0.800	0.513	4.000	0.478
P. gingivalis IgG titer^a	1.355	>0.999	0.516	0.500	0.508	0.508	1.032	0.444
P. intermedia IgG titer^a	−0.345	0.281	0.565	0.548	0.556	0.557	1.250	0.535
A. actinomycetemcomitans IgG titer^a	−0.275	0.590	0.452	0.484	0.467	0.469	0.875	0.571

Fisher’s exact test was used for statistical analysis (p < 0.05). The P. gingivalis counts was statistically significant
The area under the curve of the P. gingivalis counts was the largest amongst all markers. Subgingival plaque P. gingivalis counts specificity was higher than salivary P. gingivalis counts (0.323) [7]
EU enzyme-linked immunosorbent assay unit, AUC area under the curve
^a: J Periodontal Res. 2016 Dec;51(6):768–778

ISSN: 1472-6831