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Table 2 Methodological index for non-randomized studies (MINORS)

From: The microbial changes in subgingival plaques of orthodontic patients: a systematic review and meta-analysis of clinical trials

Minors score
Author Year 1 2 3 4 5 6 7 8 9 10 11 12 Total
Martha.et al. 2016 2 2 2 2 2 1 2 0 0 2 1 1 17
Guo.et al. 2016 2 1 2 1 1 1 2 0 0 2 1 1 14
Yáñez-Vico.et al. 2015 2 2 2 1 1 0 2 0 1 2 0 1 14
Amezquita.et al. 2006 2 1 2 2 0 1 2 0 1 1 1 1 14
Choi.et al. 2009 2 1 2 2 1 1 2 0 1 1 1 1 15
Zivkovic Sandic.et al. 2014 2 1 2 2 1 1 2 0      11
Kim.et al. 2012 2 2 2 2 1 1 2 0      12
Liu.et al. 2011 2 2 2 2 1 1 2 0      12
LoBue.et al. 2008 2 1 2 1 0 1 2 0      9
Paolantonio.et al. 1999 2 1 2 2 0 2 2 0      11
Thornberg.et al. 2009 2 2 2 1 2 2 2 0      13
Sallum.et al. 2004 2 1 2 1 1 0 2 0      9
Ristic.et al. 2008 2 1 2 2 0 1 2 0      10
  1. The items 1–12 represent: 1, a clearly stated aim; 2, inclusion of consecutive patients; 3, prospective collection of data; 4, endpoints appropriate to the aim of the study; 5, unbiased assessment of the study endpoint; 6, follow-up period appropriate to the aim of the study; 7, loss to follow-up less than 5%; 8, prospective calculation of the study size; 9, an adequate control group; 10, contemporary groups; 11, baseline equivalence of groups; and 12, adequate statistical analysis. The item scored 0 means not mentioned, 1 means reported but inadequate, and 2 means reported and adequate. The total score is 24 for cohort study and clinical controlled trial, 16 for self-controlled study