Table 5 Linkage signals with LOD ≥ 1 concordant with published findings
From: Novel caries loci in children and adults implicated by genome-wide analysis of families
Study, Gene, phenotype | Highest observed LOD Score | |||
|---|---|---|---|---|
SNP | bp | LOD | Trait | |
Genome-wide association, MPPED2, dichotomized d 1 fta in US children aged 3–12 (Shaffer et al. 2011) | rs1447267 | 30,643,586 | 1.23 | PRIM |
Association with gene set enrichment, NLRP12, dichotomized d 1 ft1 in children aged 3–12 (Wang et al. [38]) | rs11084325 | 59,424,868 | 1.12 | QTOT1 |
rs1671133 | 60,198,861 | 2.15 | QTOT2 | |