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Table 3 Logistic regression models for predicting total periodontitis (moderate and severe combined) and their performance

From: A rapid, non-invasive tool for periodontitis screening in a medical care setting

Predictor

Model 1:

Questionnaire, demographic data and biomarkers

Model 2:

Questionnaire and demographic data

Model 3:

Questionnaire only

Contributing to model

Reference

category

B

Contributing to model

Reference

category

B

Contributing to model

Reference

category

B

Predictor

 Q1. Gum disease

         

 Q2. Own teeth/gum health

+

Negative

1.800

+

Negative

1.692

+

Negative

1.686

 Q3. Gum treatment

+

Yes

1.367

+

Yes

1.286

+

Yes

1.584

 Q4. Loose teeth

+

Yes

1.774

+

Yes

1.560

+

Yes

1.969

 Q5. Lost bone

 Q6. Tooth appearance

 Q7. Floss use

 Q8. Mouthwash use

+

1–7 days

1.005

+

1–7 days

1.075

+

1–7 days

0.846

 Age (years)

+

> 39

2.206

+

> 39

2.209

   

 Sex

 Smoking

 Albumin concentration

 Chitinase activity

+

n/a

0.394

      

 Protease activity

+

n/a

0.094

      

Model performance

 AUROCC (95% CI)

0.91 (0.86–0.96)

0.88 (0.82–0.93)

0.81 (0.74–0.88)

 Predicted probability cut-off

0.662

0.678

0.623

 Hosmer-Lemeshow

0.777

0.910

0.937

 Sensitivity (95% CI), (%)

80 (71–87)

78 (69–86)

85 (78–92)

 Specificity (95% CI), (%)

88 (76–95)

84 (71–93)

63 (49–76)

 PPV (95% CI), (%)

93 (86–97)

91 (84–95)

82 (75–89)

 NPV (95% CI), (%)

69 (59–77)

66 (57–74)

68 (55–81)

  1. The table lists all candidate predictors (data presented in Table 1, Table 2, and Fig. 1). The predictors marked with a + are the ones that remained in the prediction model after stepwise backward regression modeling (see Methods section of main text). The reference category represents the response which was coded 1 in the analysis. B is the regression coefficient of the predictor, indicating its weight.
  2. n/a not applicable, AUROCC area under receiver operator characteristic curve, PPV positive predictive value, NPV negative predictive value