From: Biocompatibility of new bioactive resin composite versus calcium silicate cements: an animal study
Histopathological parameters | 1 week | 2 weeks | 4 weeks | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Control | ACTIVA | iRoot BP | MTA- HP | Control | ACTIVA | iRoot BP | MTA- HP | Control | ACTIVA | iRoot BP | MTA- HP | |
Coagulative necrosis | 1 | 2 | 3 | 2 | 1 | 1 | 3 | 2 | 0 | 0 | 1 | 1 |
Inflammatory response | 1 | 2 | 3 | 3 | 1 | 1 | 3 | 2 | 0 | 0 | 2 | 1 |
Vascular reaction | 1 | 1 | 3 | 2 | 1 | 1 | 3 | 2 | 0 | 0 | 1 | 1 |
Macrophages | 1 | 1 | 3 | 2 | 1 | 2 | 3 | 2 | 0 | 1 | 2 | 1 |
MNGCs | 0 | 0 | 2 | 1 | 0 | 1 | 3 | 2 | 0 | 0 | 1 | 1 |
Angiogenesis | 1 | 2 | 1 | 1 | 1 | 1 | 3 | 2 | 0 | 1 | 1 | 1 |
Fibrosis | 1 | 1 | 2 | 2 | 1 | 1 | 3 | 2 | 0 | 1 | 2 | 1 |
Thickness of fibrous capsule (μm) | 142.08±32.79 | 235.14±27.39 | 460.99±33.86 | 352.72±44.45 | 169.43±39.90 | 180.90±43.49 | 410.52±75.69 | 289.56±62.44 | 109.89±30.48 | 132.55±34.79 | 270.90±56.87 | 197.93±31.14 |