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Table 4 Mean CLR OTUs for each of 267 bacterial species in the overall cohort and by age categories, and its linear correlation with age

From: Composition and diversity of the subgingival microbiome and its relationship with age in postmenopausal women: an epidemiologic investigation

Rank Order*

OTU Label

Culture Status

Socransky Complex

Overall

Cohort

(N = 1219)

Age Categories (years)

Linear Correlation

    

CLR OTU

Mean (SE)

50–59

(N = 239)

CLR OTU

Mean (SE)

60–69

(N = 554)

CLR OTU

Mean (SE)

≥70

(N = 426)

CLR OTU

Mean (SE)

p-value

Pearson r

p-value

1

Veillonella dispar

N

–

8.25 (0.06)

8.23 (0.13)

8.11 (0.09)

8.45 (0.10)

0.045

0.08

0.008

2

Streptococcus oralis

N

Y

8.06 (0.05)

8.40 (0.11)

8.06 (0.08)

7.87 (0.09)

0.002

−0.10

<.001

3

Veillonella parvula

N

P

7.60 (0.07)

7.48 (0.15)

7.45 (0.09)

7.86 (0.11)

0.014

0.10

0.001

4

Fusobacterium nucleatum_subsp._vincentii

N

O

6.43 (0.08)

6.21 (0.17)

6.48 (0.11)

6.50 (0.13)

0.356

0.02

0.587

5

Selenomonas sputigena

N

–

5.63 (0.08)

5.34 (0.17)

5.44 (0.12)

6.03 (0.14)

0.001

0.10

<.001

6

Fusobacterium nucleatum_subsp._animalis

N

–

5.39 (0.07)

5.29 (0.14)

5.29 (0.10)

5.57 (0.12)

0.136

0.10

0.106

7

Campylobacter gracilis

N

O

5.19 (0.05)

5.02 (0.11)

5.15 (0.07)

5.33 (0.09)

0.052

0.10

0.016

8

Fusobacterium nucleatum_subsp._polymorphum

N

O

5.19 (0.07)

5.36 (0.15)

5.28 (0.09)

4.97 (0.12)

0.052

−0.10

0.019

9

Prevotella oris

N

–

5.08 (0.09)

5.25 (0.18)

5.05 (0.13)

5.03 (0.16)

0.646

−0.10

0.118

10

Streptococcus sanguinis

N

Y

4.91 (0.07)

5.57 (0.15)

5.04 (0.10)

4.38 (0.13)

<.001*

−0.18

<.001*

11

Corynebacterium matruchotii

N

–

4.81 (0.07)

4.87 (0.17)

4.86 (0.10)

4.70 (0.12)

0.550

−0.04

0.171

12

Selenomonas noxia

N

–

4.81 (0.08)

4.63 (0.18)

4.69 (0.11)

5.06 (0.13)

0.049

0.10

<.001

13

Prevotella nigrescens

N

O

4.31 (0.10)

4.48 (0.21)

4.28 (0.15)

4.26 (0.18)

0.714

−0.03

0.370

14

Parvimonas micra

N

–

4.29 (0.08)

4.08 (0.17)

4.35 (0.11)

4.33 (0.12)

0.401

0.00

0.967

15

Rothia dentocariosa

U

–

4.28 (0.09)

4.46 (0.19)

4.38 (0.13)

4.04 (0.15)

0.113

−0.10

0.008

16

Fusobacterium sp._oral_taxon_203

N

–

4.23 (0.10)

4.08 (0.22)

4.36 (0.15)

4.16 (0.17)

0.497

−0.01

0.713

17

Streptococcus gordonii

N

Y

4.19 (0.08)

3.93 (0.18)

4.15 (0.12)

4.40 (0.13)

0.090

0.04

0.039

18

Granulicatella adiacens

N

–

4.15 (0.06)

4.23 (0.14)

4.11 (0.09)

4.15 (0.10)

0.749

0.00

0.991

19

Streptococcus intermedius

N

Y

3.94 (0.10)

4.33 (0.21)

3.86 (0.15)

3.81 (0.16)

0.119

−0.10

0.016

20

Actinomyces naeslundii

N

B

3.85 (0.06)

4.00 (0.14)

3.88 (0.09)

3.72 (0.11)

0.230

−0.10

0.008

21

TM7_[G-1] sp._oral_taxon_346

P

–

3.78 (0.09)

3.63 (0.19)

3.90 (0.12)

3.70 (0.16)

0.421

0.00

0.917

22

Haemophilus parainfluenzae

N

–

3.74 (0.09)

4.21 (0.19)

3.73 (0.13)

3.48 (0.15)

0.014

−0.10

0.004

23

Fusobacterium naviforme

N

–

3.58 (0.08)

3.61 (0.18)

3.62 (0.12)

3.52 (0.14)

0.852

−0.03

0.294

24

Dialister invisus

N

–

3.51 (0.08)

3.12 (0.16)

3.50 (0.11)

3.75 (0.13)

0.013

0.10

0.003

25

Capnocytophaga gingivalis

N

G

3.36 (0.08)

3.39 (0.18)

3.45 (0.11)

3.23 (0.13)

0.423

−0.04

0.172

26

Streptococcus cristatus

N

–

3.27 (0.07)

3.17 (0.16)

3.27 (0.11)

3.32 (0.13)

0.776

0.01

0.754

27

Gemella morbillorum

N

–

3.14 (0.09)

3.37 (0.20)

3.35 (0.13)

2.73 (0.16)

0.004

−0.11

<.001*

28

Streptococcus salivarius

U

–

3.02 (0.08)

3.05 (0.18)

2.79 (0.13)

3.29 (0.14)

0.028

0.10

0.090

29

TM7_[G-1] sp._oral_taxon_349

N

–

2.99 (0.10)

2.71 (0.22)

3.15 (0.14)

2.95 (0.18)

0.251

0.04

0.204

30

Bacteroidales_[G-2] sp._oral_taxon_274

N

–

2.96 (0.10)

2.47 (0.22)

3.15 (0.14)

3.00 (0.16)

0.030

0.03

0.328

31

Campylobacter showae

P

O

2.89 (0.08)

3.00 (0.17)

2.81 (0.11)

2.93 (0.14)

0.609

−0.01

0.685

32

Veillonella atypica

N

–

2.88 (0.09)

2.47 (0.20)

2.56 (0.13)

3.53 (0.14)

<.001*

0.16

<.001*

33

Eikenella corrodens

N

–

2.87 (0.07)

3.00 (0.15)

3.07 (0.10)

2.53 (0.12)

0.001

−0.11

<.001*

34

Capnocytophaga leadbetteri

N

–

2.86 (0.09)

2.87 (0.20)

2.93 (0.13)

2.78 (0.16)

0.758

−0.03

0.334

35

Fretibacterium sp._oral_taxon_360

N

–

2.81 (0.11)

2.29 (0.23)

2.89 (0.16)

3.00 (0.19)

0.048

0.04

0.148

36

Prevotella sp._oral_taxon_317

N

–

2.73 (0.10)

2.79 (0.22)

2.68 (0.16)

2.76 (0.18)

0.907

−0.00

0.965

37

Capnocytophaga granulosa

U

–

2.72 (0.09)

2.39 (0.21)

2.84 (0.13)

2.75 (0.16)

0.189

0.04

0.152

38

Alloprevotella tannerae

N

–

2.71 (0.12)

2.69 (0.24)

2.78 (0.17)

2.64 (0.20)

0.865

0.01

0.788

39

Kingella oralis

P

–

2.66 (0.08)

2.66 (0.19)

2.65 (0.11)

2.68 (0.14)

0.983

−0.01

0.847

40

TM7_[G-1] sp._oral_taxon_952

U

–

2.58 (0.10)

2.80 (0.22)

2.83 (0.14)

2.12 (0.16)

0.002

−0.10

<.001

41

Selenomonas artemidis

N

–

2.51 (0.11)

2.77 (0.24)

2.39 (0.16)

2.52 (0.19)

0.419

−0.00

0.957

42

Campylobacter concisus

N

G

2.41 (0.06)

2.22 (0.14)

2.37 (0.10)

2.56 (0.11)

0.152

0.10

0.036

43

Actinomyces oris

N

B

2.36 (0.08)

2.63 (0.17)

2.37 (0.11)

2.18 (0.13)

0.104

−0.10

0.021

44

Treponema socranskii

N

–

2.22 (0.07)

1.84 (0.17)

2.16 (0.11)

2.52 (0.13)

0.004

0.10

<.001

45

Cardiobacterium hominis

N

–

2.21 (0.08)

2.50 (0.19)

2.45 (0.12)

1.75 (0.14)

<.001*

−0.11

<.001

46

Leptotrichia wadei

N

–

2.15 (0.10)

2.21 (0.23)

1.94 (0.16)

2.38 (0.18)

0.159

0.03

0.305

47

Anaeroglobus geminatus

P

–

2.12 (0.10)

1.32 (0.22)

1.94 (0.15)

2.79 (0.18)

<.001*

0.17

<.001*

48

Gemella haemolysans

N

–

2.11 (0.09)

2.42 (0.20)

2.10 (0.13)

1.96 (0.14)

0.161

−0.10

0.018

49

Capnocytophaga sputigena

N

G

2.11 (0.09)

2.31 (0.21)

2.23 (0.13)

1.84 (0.17)

0.113

−0.10

0.094

50

Rothia aeria

N

–

2.11 (0.09)

2.49 (0.20)

2.42 (0.14)

1.48 (0.15)

<.001*

−0.15

<.001*

51

Bergeyella sp._oral_taxon_322

N

–

2.08 (0.07)

2.38 (0.16)

2.11 (0.10)

1.87 (0.11)

0.028

−0.10

0.008

52

Leptotrichia hongkongensis

N

–

2.02 (0.09)

2.02 (0.21)

1.94 (0.14)

2.13 (0.16)

0.660

0.03

0.337

53

Rothia mucilaginosa

U

–

1.95 (0.08)

1.79 (0.17)

1.90 (0.11)

2.09 (0.13)

0.321

0.03

0.237

54

Prevotella melaninogenica

N

–

1.90 (0.08)

1.75 (0.17)

1.78 (0.12)

2.14 (0.14)

0.095

0.10

0.049

55

Actinomyces sp._oral_taxon_169

N

–

1.89 (0.09)

2.28 (0.20)

1.96 (0.13)

1.59 (0.15)

0.016

−0.10

<.001

56

Tannerella forsythia

N

R

1.87 (0.10)

1.50 (0.21)

1.80 (0.14)

2.18 (0.17)

0.042

0.10

0.029

57

Selenomonas sp._oral_taxon_136

N

–

1.86 (0.08)

1.21 (0.18)

1.76 (0.12)

2.36 (0.15)

<.001*

0.16

<.001*

58

Catonella morbi

N

–

1.86 (0.08)

2.08 (0.17)

1.89 (0.11)

1.69 (0.13)

0.184

−0.10

0.020

59

Prevotella denticola

N

–

1.74 (0.10)

1.46 (0.23)

1.60 (0.15)

2.10 (0.18)

0.040

0.10

0.006

60

Neisseria sicca

N

–

1.72 (0.11)

1.58 (0.25)

1.88 (0.16)

1.60 (0.18)

0.416

−0.01

0.678

61

Peptostreptococcaceae_[XI][G-9] [Eubacterium]_brac

U

–

1.70 (0.08)

2.08 (0.16)

1.72 (0.12)

1.47 (0.14)

0.030

−0.10

0.003

62

Neisseria elongata

N

–

1.63 (0.10)

1.95 (0.25)

1.81 (0.15)

1.22 (0.17)

0.012

−0.10

0.008

63

Cardiobacterium valvarum

U

–

1.49 (0.09)

1.60 (0.21)

1.63 (0.13)

1.26 (0.14)

0.137

−0.10

0.044

64

Porphyromonas sp._oral_taxon_279

P

–

1.49 (0.09)

1.46 (0.20)

1.62 (0.13)

1.34 (0.16)

0.394

−0.02

0.494

65

Selenomonas infelix

U

–

1.48 (0.08)

1.56 (0.17)

1.44 (0.12)

1.50 (0.15)

0.871

−0.01

0.709

66

Leptotrichia sp._oral_taxon_212

U

–

1.44 (0.09)

1.63 (0.21)

1.64 (0.13)

1.08 (0.16)

0.013

−0.10

0.011

67

Actinomyces sp._oral_taxon_180

N

–

1.44 (0.07)

1.54 (0.15)

1.45 (0.10)

1.38 (0.11)

0.704

−0.03

0.235

68

Prevotella sp._oral_taxon_300

N

–

1.43 (0.09)

1.31 (0.19)

1.24 (0.13)

1.75 (0.15)

0.025

0.10

0.007

69

Prevotella maculosa

N

–

1.42 (0.08)

1.07 (0.17)

1.32 (0.11)

1.75 (0.13)

0.003

0.10

0.001

70

Streptococcus mutans

N

–

1.39 (0.11)

0.98 (0.24)

1.19 (0.16)

1.87 (0.20)

0.005

0.10

<.001

71

Actinomyces massiliensis

N

B

1.38 (0.07)

1.68 (0.17)

1.50 (0.10)

1.05 (0.11)

0.002

−0.12

<.001*

72

Fretibacterium fastidiosum

N

–

1.30 (0.10)

1.12 (0.22)

1.25 (0.15)

1.47 (0.17)

0.393

0.04

0.173

73

Veillonellaceae_[G-1] sp._oral_taxon_150

N

–

1.23 (0.09)

0.74 (0.20)

1.00 (0.13)

1.81 (0.16)

<.001*

0.14

<.001*

74

Neisseria flavescens

N

–

1.23 (0.10)

0.98 (0.21)

1.28 (0.14)

1.30 (0.17)

0.425

0.02

0.533

75

Prevotella oulorum

P

–

1.22 (0.09)

1.23 (0.20)

1.00 (0.13)

1.50 (0.15)

0.041

0.10

0.059

76

Streptococcus anginosus

N

Y

1.17 (0.11)

1.03 (0.23)

0.92 (0.16)

1.56 (0.19)

0.024

0.10

0.013

77

Lachnoanaerobaculum saburreum

N

–

1.07 (0.08)

0.85 (0.18)

1.12 (0.12)

1.13 (0.14)

0.384

0.04

0.208

78

Veillonellaceae_[G-1] sp._oral_taxon_155

N

–

1.00 (0.09)

0.66 (0.20)

0.84 (0.13)

1.39 (0.15)

0.004

0.10

<.001

79

Selenomonas sp._oral_taxon_892

L

–

0.98 (0.08)

1.18 (0.19)

1.05 (0.12)

0.76 (0.15)

0.148

−0.10

0.030

80

Actinomyces johnsonii

N

B

0.97 (0.07)

1.18 (0.16)

0.92 (0.11)

0.92 (0.12)

0.365

−0.04

0.229

81

Selenomonas sp._oral_taxon_137

U

–

0.95 (0.11)

0.95 (0.25)

1.21 (0.17)

0.61 (0.20)

0.064

−0.04

0.145

82

Corynebacterium durum

U

–

0.93 (0.08)

1.53 (0.19)

1.07 (0.12)

0.42 (0.13)

<.001*

−0.15

<.001*

83

Lautropia mirabilis

U

–

0.88 (0.09)

1.28 (0.21)

0.99 (0.13)

0.53 (0.15)

0.006

−0.10

<.001

84

Veillonella rogosae

N

–

0.87 (0.09)

1.06 (0.20)

1.08 (0.13)

0.49 (0.16)

0.010

−0.10

<.001

85

Leptotrichia sp._oral_taxon_417

N

–

0.86 (0.09)

0.41 (0.20)

0.95 (0.13)

1.01 (0.16)

0.048

0.10

0.006

86

Selenomonas flueggei

N

–

0.81 (0.08)

0.58 (0.18)

0.81 (0.12)

0.93 (0.14)

0.317

0.04

0.122

87

Selenomonas sp._oral_taxon_134

P

–

0.77 (0.10)

0.55 (0.21)

0.75 (0.14)

0.94 (0.18)

0.367

0.03

0.251

88

Streptococcus parasanguinis_II

U

–

0.74 (0.09)

0.58 (0.19)

0.49 (0.13)

1.15 (0.15)

0.003

0.11

<.001*

89

Megasphaera micronuciformis

N

–

0.70 (0.08)

0.47 (0.19)

0.46 (0.13)

1.14 (0.14)

<.001

0.12

<.001*

90

Capnocytophaga sp._oral_taxon_336

N

–

0.69 (0.09)

0.68 (0.19)

0.69 (0.13)

0.71 (0.16)

0.991

0.02

0.480

91

Oribacterium sp._oral_taxon_078

U

–

0.66 (0.08)

−0.03 (0.17)

0.51 (0.11)

1.26 (0.14)

<.001*

0.18

<.001*

92

Actinomyces sp._oral_taxon_171

P

–

0.66 (0.08)

0.82 (0.18)

0.66 (0.12)

0.57 (0.13)

0.527

−0.10

0.090

93

Lachnospiraceae_[G-3] sp._oral_taxon_100

U

–

0.59 (0.08)

0.60 (0.18)

0.73 (0.12)

0.41 (0.14)

0.200

−0.03

0.239

94

Parvimonas sp._oral_taxon_393

U

–

0.58 (0.11)

1.11 (0.24)

0.63 (0.16)

0.22 (0.17)

0.010

−0.12

<.001*

95

Actinomyces gerencseriae

N

B

0.56 (0.07)

0.49 (0.17)

0.37 (0.11)

0.86 (0.13)

0.012

0.10

0.008

96

Dialister pneumosintes

P

–

0.55 (0.09)

0.64 (0.20)

0.42 (0.14)

0.65 (0.16)

0.477

0.03

0.357

97

Kingella denitrificans

N

–

0.54 (0.09)

0.21 (0.20)

0.45 (0.13)

0.84 (0.15)

0.025

0.10

0.024

98

Porphyromonas endodontalis

N

–

0.52 (0.12)

1.09 (0.27)

0.56 (0.17)

0.13 (0.20)

0.015

−0.10

<.001

99

TM7_[G-5] sp._oral_taxon_356

P

–

0.49 (0.11)

0.30 (0.23)

0.61 (0.16)

0.43 (0.19)

0.517

0.02

0.580

100

Selenomonas sp._oral_taxon_919

U

–

0.47 (0.08)

0.72 (0.18)

0.45 (0.12)

0.35 (0.15)

0.287

−0.10

0.096

101

Leptotrichia buccalis

N

–

0.45 (0.10)

0.23 (0.23)

0.77 (0.14)

0.16 (0.16)

0.011

−0.03

0.375

102

Prevotella sp._oral_taxon_472

N

–

0.45 (0.10)

0.65 (0.23)

0.80 (0.15)

−0.13 (0.17)

<.001*

−0.10

<.001

103

Capnocytophaga sp._oral_taxon_326

P

–

0.41 (0.10)

0.38 (0.23)

0.62 (0.15)

0.15 (0.17)

0.121

−0.10

0.080

104

Streptococcus constellatus

N

O

0.35 (0.10)

0.25 (0.21)

0.18 (0.15)

0.63 (0.17)

0.114

0.04

0.139

105

Prevotella salivae

N

–

0.34 (0.08)

−0.22 (0.18)

0.32 (0.12)

0.69 (0.14)

<.001

0.15

<.001*

106

Leptotrichia sp._oral_taxon_392

U

–

0.33 (0.09)

0.49 (0.20)

0.58 (0.13)

− 0.08 (0.15)

0.003

−0.10

0.001

107

Actinobaculum sp._oral_taxon_183

N

–

0.32 (0.08)

0.29 (0.17)

0.28 (0.12)

0.40 (0.14)

0.765

0.01

0.742

108

Neisseria oralis

U

–

0.31 (0.11)

0.47 (0.25)

0.35 (0.15)

0.19 (0.18)

0.618

−0.04

0.133

109

Atopobium rimae

N

–

0.21 (0.09)

−0.08 (0.19)

0.17 (0.13)

0.43 (0.16)

0.124

0.10

0.108

110

Leptotrichia hofstadii

N

–

0.20 (0.10)

0.10 (0.22)

0.27 (0.15)

0.17 (0.17)

0.804

0.01

0.743

111

Streptococcus sp._oral_taxon_074

N

–

0.15 (0.07)

0.15 (0.16)

0.25 (0.11)

0.02 (0.12)

0.340

−0.04

0.154

112

Fretibacterium sp._oral_taxon_359

L

–

0.15 (0.11)

0.14 (0.25)

0.04 (0.16)

0.30 (0.18)

0.537

0.02

0.552

113

Leptotrichia shahii

U

–

0.11 (0.10)

0.30 (0.22)

−0.09 (0.15)

0.26 (0.19)

0.209

0.03

0.298

114

Tannerella sp._oral_taxon_286

U

–

0.11 (0.07)

− 0.15 (0.16)

0.26 (0.10)

0.06 (0.13)

0.101

0.03

0.370

115

Porphyromonas sp._oral_taxon_284

N

–

0.08 (0.10)

0.14 (0.21)

0.22 (0.14)

− 0.14 (0.16)

0.223

−0.10

0.080

116

Peptostreptococcaceae_[XI][G-7] [Eubacterium]_yuri

P

–

0.05 (0.10)

0.50 (0.21)

0.19 (0.14)

−0.40 (0.16)

0.001

−0.14

<.001*

117

Selenomonas sp._oral_taxon_146

L

–

0.04 (0.08)

0.04 (0.18)

− 0.03 (0.12)

0.14 (0.14)

0.659

0.014

0.633

118

Fusobacterium periodonticum

N

O

−0.02 (0.07)

−0.12 (0.16)

0.13 (0.11)

−0.17 (0.13)

0.174

−0.02

0.488

119

Actinomyces meyeri

L

B

−0.04 (0.08)

0.29 (0.18)

0.05 (0.12)

− 0.35 (0.13)

0.010

−0.11

<.001*

120

Leptotrichia sp._oral_taxon_215

N

–

− 0.05 (0.08)

0.16 (0.18)

0.01 (0.12)

− 0.24 (0.14)

0.157

−0.04

0.170

121

Prevotella oralis

N

–

− 0.06 (0.10)

−0.34 (0.20)

− 0.13 (0.14)

0.20 (0.17)

0.105

0.10

0.030

122

Prevotella pleuritidis

N

–

− 0.10 (0.12)

−0.07 (0.27)

0.09 (0.18)

−0.38 (0.20)

0.211

−0.04

0.190

123

Abiotrophia defectiva

N

–

−0.15 (0.09)

−0.05 (0.19)

− 0.01 (0.13)

− 0.38 (0.14)

0.138

− 0.10

0.028

124

Gemella sanguinis

N

–

−0.19 (0.07)

−0.16 (0.15)

− 0.35 (0.10)

− 0.00 (0.12)

0.077

0.04

0.204

125

Fusobacterium nucleatum_subsp._nucleatum

N

O

−0.25 (0.08)

−0.44 (0.17)

− 0.30 (0.11)

− 0.08 (0.14)

0.209

0.03

0.259

126

Atopobium parvulum

N

–

− 0.25 (0.08)

−0.28 (0.17)

− 0.47 (0.11)

0.06 (0.14)

0.009

0.10

0.005

127

Aggregatibacter sp._oral_taxon_458

N

–

− 0.25 (0.09)

− 0.11 (0.19)

− 0.17 (0.13)

− 0.44 (0.15)

0.309

−0.10

0.047

128

Streptococcus parasanguinis_I

N

–

− 0.26 (0.08)

−0.29 (0.17)

− 0.48 (0.11)

0.05 (0.13)

0.008

0.10

0.008

129

Aggregatibacter aphrophilus

N

–

− 0.27 (0.11)

−0.18 (0.25)

− 0.01 (0.17)

− 0.66 (0.18)

0.027

− 0.10

0.015

130

Treponema denticola

N

R

−0.28 (0.10)

−0.16 (0.22)

− 0.25 (0.15)

− 0.39 (0.18)

0.692

− 0.04

0.211

131

Prevotella saccharolytica

U

–

− 0.37 (0.07)

− 0.38 (0.16)

− 0.26 (0.11)

− 0.51 (0.13)

0.336

− 0.01

0.663

132

TM7_[G-1] sp._oral_taxon_488

P

–

− 0.39 (0.10)

− 0.39 (0.22)

− 0.11 (0.15)

− 0.76 (0.16)

0.015

−0.04

0.132

133

Johnsonella ignava

U

–

− 0.41 (0.09)

−0.50 (0.21)

− 0.34 (0.14)

− 0.45 (0.16)

0.783

− 0.01

0.783

134

Actinomyces israelii

N

B

−0.47 (0.06)

−0.65 (0.13)

− 0.52 (0.09)

− 0.30 (0.11)

0.091

0.10

0.012

135

Lachnoanaerobaculum umeaense

P

–

− 0.47 (0.07)

−0.35 (0.17)

− 0.39 (0.11)

− 0.65 (0.12)

0.198

−0.03

0.316

136

Streptococcus sp._oral_taxon_056

U

–

− 0.49 (0.08)

−0.38 (0.19)

− 0.37 (0.12)

− 0.73 (0.14)

0.127

−0.04

0.050

137

Olsenella sp._oral_taxon_807

N

–

− 0.49 (0.07)

−0.93 (0.15)

− 0.50 (0.10)

− 0.25 (0.12)

0.002

0.11

<.001*

138

Solobacterium moorei

U

–

− 0.51 (0.06)

−0.49 (0.15)

− 0.60 (0.09)

− 0.42 (0.11)

0.437

0.04

0.221

139

Treponema maltophilum

P

–

− 0.53 (0.08)

−0.78 (0.16)

− 0.59 (0.11)

− 0.32 (0.13)

0.070

0.10

0.040

140

TM7_[G-1] sp._oral_taxon_348

N

–

− 0.53 (0.08)

− 0.66 (0.17)

− 0.29 (0.13)

− 0.77 (0.14)

0.026

− 0.03

0.373

141

Porphyromonas gingivalis

N

R

−0.56 (0.12)

−0.70 (0.26)

− 0.60 (0.17)

− 0.43 (0.22)

0.688

0.03

0.348

142

Centipeda periodontii

N

–

− 0.60 (0.08)

− 0.94 (0.15)

− 0.55 (0.11)

− 0.47 (0.13)

0.074

0.06

0.031

143

Selenomonas sp._oral_taxon_126

N

–

− 0.60 (0.08)

−0.77 (0.18)

− 0.56 (0.12)

− 0.56 (0.14)

0.588

0.03

0.386

144

Desulfobulbus sp._oral_taxon_041

U

–

−0.66 (0.10)

−1.02 (0.20)

− 0.70 (0.14)

− 0.40 (0.17)

0.064

0.10

0.027

145

Alloprevotella rava

U

–

−0.68 (0.08)

−0.78 (0.18)

− 0.64 (0.12)

− 0.69 (0.14)

0.809

0.02

0.464

146

Actinobaculum sp._oral_taxon_848

P

–

− 0.70 (0.08)

−0.83 (0.17)

− 0.82 (0.11)

−0.46 (0.13)

0.080

0.10

0.016

147

Stomatobaculum longum

N

–

− 0.70 (0.07)

− 0.95 (0.16)

− 0.76 (0.11)

−0.48 (0.13)

0.054

0.11

<.001

148

Prevotella histicola

N

–

− 0.75 (0.09)

− 0.96 (0.18)

−1.04 (0.13)

− 0.26 (0.16)

<.001

0.11

<.001*

149

Aggregatibacter segnis

U

–

− 0.79 (0.10)

− 0.42 (0.22)

− 0.69 (0.14)

−1.13 (0.15)

0.020

− 0.11

<.001*

150

Leptotrichia sp._oral_taxon_225

N

–

− 0.80 (0.10)

− 0.43 (0.22)

− 0.60 (0.15)

− 1.25 (0.15)

0.002

− 0.11

<.001*

151

Ruminococcaceae_[G-1] sp._oral_taxon_075

N

–

− 0.80 (0.08)

− 0.79 (0.17)

− 0.69 (0.12)

−0.94 (0.13)

0.350

−0.03

0.341

152

Peptostreptococcus stomatis

U

–

− 0.80 (0.09)

−0.50 (0.19)

− 0.77 (0.13)

− 1.02 (0.14)

0.085

− 0.10

0.032

153

Porphyromonas catoniae

P

–

− 0.92 (0.09)

− 0.50 (0.20)

− 0.79 (0.13)

−1.31 (0.14)

0.002

− 0.10

<.001

154

Actinomyces sp._oral_taxon_178

P

–

−0.93 (0.06)

− 1.15 (0.14)

− 0.94 (0.09)

− 0.78 (0.10)

0.099

0.05

0.080

155

Prevotella pallens

N

–

− 0.93 (0.08)

−1.00 (0.17)

− 1.05 (0.11)

−0.73 (0.14)

0.191

0.10

0.054

156

Filifactor alocis

U

–

− 0.94 (0.10)

−0.66 (0.23)

− 0.98 (0.15)

− 1.05 (0.18)

0.382

− 0.10

0.077

157

Selenomonas sp._oral_taxon_936

P

–

−0.96 (0.08)

− 0.91 (0.17)

−1.05 (0.12)

− 0.87 (0.14)

0.578

0.03

0.323

158

TM7_[G-1] sp._oral_taxon_347

N

–

− 0.97 (0.09)

−0.64 (0.20)

− 0.95 (0.14)

−1.17 (0.14)

0.107

− 0.10

0.071

159

Haemophilus sp._oral_taxon_036

N

–

−1.01 (0.09)

− 0.65 (0.19)

− 1.00 (0.13)

− 1.21 (0.15)

0.075

− 0.10

0.002

160

Prevotella sp._oral_taxon_292

P

–

− 1.06 (0.08)

− 1.34 (0.17)

− 1.15 (0.12)

−0.79 (0.15)

0.040

0.10

0.001

161

Leptotrichia sp._oral_taxon_498

N

–

− 1.07 (0.09)

−1.28 (0.20)

− 1.20 (0.13)

−0.77 (0.16)

0.059

0.10

0.013

162

Capnocytophaga sp._oral_taxon_338

U

–

− 1.08 (0.09)

−1.17 (0.20)

− 1.12 (0.13)

−0.98 (0.15)

0.671

0.01

0.808

163

Alloprevotella sp._oral_taxon_308

N

–

− 1.14 (0.07)

−0.90 (0.14)

−1.28 (0.10)

− 1.10 (0.12)

0.111

−0.01

0.799

164

Treponema sp._oral_taxon_231

P

–

− 1.15 (0.09)

−1.04 (0.18)

− 1.03 (0.13)

− 1.36 (0.15)

0.206

− 0.10

0.074

165

TM7_[G-1] sp._oral_taxon_352

N

–

− 1.15 (0.07)

− 1.31 (0.15)

− 1.11 (0.10)

− 1.11 (0.12)

0.545

0.04

0.173

166

Prevotella buccae

U

–

− 1.23 (0.07)

−1.71 (0.14)

− 1.36 (0.11)

− 0.78 (0.12)

<.001*

0.14

<.001*

167

Prevotella loescheii

N

–

−1.24 (0.09)

−0.96 (0.21)

−0.97 (0.14)

− 1.74 (0.15)

<.001

− 0.10

0.001

168

Capnocytophaga sp._oral_taxon_864

U

–

− 1.27 (0.08)

−0.98 (0.20)

−1.15 (0.13)

− 1.57 (0.13)

0.020

− 0.10

0.005

169

Actinomyces sp._oral_taxon_170

U

–

−1.29 (0.08)

− 0.99 (0.19)

− 1.16 (0.13)

− 1.62 (0.13)

0.011

− 0.10

<.001

170

Lachnoanaerobaculum orale

U

–

− 1.31 (0.07)

− 1.09 (0.16)

− 1.46 (0.09)

−1.23 (0.12)

0.085

0.02

0.513

171

Ottowia sp._oral_taxon_894

N

–

− 1.31 (0.08)

−1.44 (0.18)

− 1.24 (0.12)

− 1.33 (0.14)

0.662

−0.00

0.938

172

Streptococcus lactarius

N

–

− 1.32 (0.07)

− 1.06 (0.15)

− 1.46 (0.10)

− 1.30 (0.12)

0.097

−0.02

0.414

173

Peptostreptococcaceae_[XI][G-1] [Eubacterium]_infi

P

–

− 1.33 (0.07)

− 1.59 (0.15)

− 1.41 (0.09)

− 1.08 (0.12)

0.014

0.10

0.002

174

Leptotrichia sp._oral_taxon_219

N

–

− 1.34 (0.07)

−1.39 (0.17)

− 1.27 (0.11)

−1.39 (0.12)

0.736

−0.01

0.717

175

Prevotella intermedia

P

O

−1.36 (0.11)

−1.31 (0.25)

− 1.35 (0.17)

− 1.41 (0.18)

0.943

−0.04

0.181

176

Veillonella denticariosi

U

–

− 1.37 (0.09)

− 1.51 (0.19)

− 1.39 (0.13)

− 1.27 (0.15)

0.621

0.04

0.156

177

Fretibacterium sp._oral_taxon_362

N

–

− 1.43 (0.08)

−1.48 (0.19)

− 1.43 (0.12)

− 1.42 (0.14)

0.965

0.00

0.888

178

Bacteroidetes_[G-5] sp._oral_taxon_511

U

–

− 1.47 (0.09)

− 1.44 (0.19)

− 1.43 (0.14)

− 1.54 (0.15)

0.846

−0.03

0.378

179

Prevotella sp._oral_taxon_313

P

–

− 1.49 (0.08)

−1.14 (0.18)

− 1.75 (0.11)

− 1.35 (0.14)

0.007

0.02

0.431

180

TM7_[G-3] sp._oral_taxon_351

P

–

− 1.50 (0.06)

−1.84 (0.13)

− 1.39 (0.10)

− 1.45 (0.11)

0.029

0.10

0.018

181

Streptococcus australis

N

–

− 1.51 (0.07)

−1.62 (0.15)

− 1.57 (0.11)

− 1.38 (0.13)

0.373

0.03

0.295

182

Granulicatella elegans

N

–

− 1.59 (0.07)

−1.18 (0.17)

− 1.72 (0.11)

−1.65 (0.12)

0.023

−0.10

0.067

183

TM7_[G-1] sp._oral_taxon_869

P

–

− 1.60 (0.09)

−1.64 (0.20)

− 1.55 (0.14)

− 1.64 (0.15)

0.890

0.01

0.663

184

Capnocytophaga sp._oral_taxon_902

N

–

−1.65 (0.08)

− 1.56 (0.19)

− 1.68 (0.12)

−1.67 (0.14)

0.860

−0.04

0.220

185

Prevotella dentalis

P

–

−1.66 (0.08)

−1.65 (0.19)

− 1.82 (0.12)

−1.47 (0.14)

0.180

0.03

0.326

186

Campylobacter curvus

N

–

− 1.67 (0.07)

−1.57 (0.17)

− 1.79 (0.10)

− 1.58 (0.13)

0.365

0.03

0.335

187

Pseudoramibacter alactolyticus

P

–

− 1.68 (0.08)

− 2.18 (0.17)

−1.73 (0.12)

− 1.35 (0.15)

0.001

0.12

<.001*

188

TM7_[G-6] sp._oral_taxon_870

N

–

− 1.71 (0.08)

−1.47 (0.18)

− 1.69 (0.12)

− 1.85 (0.13)

0.220

−0.10

0.085

189

Veillonellaceae_[G-1] sp._oral_taxon_129

N

–

− 1.71 (0.08)

− 1.96 (0.16)

− 1.80 (0.11)

− 1.46 (0.14)

0.042

0.10

0.010

190

Tannerella sp._oral_taxon_808

U

–

− 1.75 (0.07)

−2.03 (0.14)

−1.70 (0.10)

− 1.65 (0.12)

0.104

0.10

0.011

191

Peptostreptococcaceae_[XI][G-6] [Eubacterium]_noda

L

–

− 1.75 (0.08)

− 1.67 (0.18)

− 1.90 (0.11)

−1.61 (0.14)

0.238

0.02

0.425

192

Mitsuokella sp._oral_taxon_131

N

–

− 1.79 (0.09)

−2.18 (0.17)

− 1.96 (0.13)

− 1.36 (0.16)

<.001

0.14

<.001*

193

Mycoplasma salivarium

P

–

− 1.80 (0.07)

−1.77 (0.15)

− 1.87 (0.11)

− 1.71 (0.12)

0.579

0.03

0.302

194

Haemophilus haemolyticus

P

–

− 1.81 (0.08)

−1.30 (0.19)

− 1.92 (0.12)

− 1.94 (0.12)

0.006

−0.10

0.043

195

Bergeyella sp._oral_taxon_907

P

–

−1.81 (0.07)

−1.86 (0.15)

− 1.72 (0.10)

− 1.92 (0.12)

0.405

− 0.01

0.765

196

TM7_[G-2] sp._oral_taxon_350

N

–

− 1.82 (0.09)

− 1.86 (0.18)

− 1.82 (0.13)

− 1.80 (0.15)

0.968

0.02

0.412

197

Prevotella veroralis

U

–

− 1.82 (0.08)

−1.73 (0.18)

− 1.78 (0.13)

− 1.93 (0.13)

0.582

−0.02

0.413

198

Aggregatibacter paraphrophilus

N

–

− 1.82 (0.09)

−1.48 (0.21)

− 1.69 (0.14)

−2.19 (0.13)

0.007

−0.10

<.001

199

Leptotrichia sp._oral_taxon_223

P

–

− 1.82 (0.08)

−1.71 (0.17)

− 1.98 (0.11)

− 1.69 (0.14)

0.206

0.02

0.499

200

Bifidobacterium dentium

N

–

− 1.85 (0.08)

−2.10 (0.18)

−2.12 (0.12)

−1.37 (0.15)

<.001*

0.15

<.001*

201

Alloprevotella sp._oral_taxon_473

U

–

− 1.87 (0.08)

−1.63 (0.17)

− 1.88 (0.12)

− 1.98 (0.13)

0.300

−0.10

0.030

202

Veillonellaceae_[G-1] sp._oral_taxon_145

U

–

− 1.88 (0.08)

−1.98 (0.16)

− 1.83 (0.12)

− 1.88 (0.14)

0.768

0.02

0.551

203

Neisseria bacilliformis

N

–

−1.89 (0.09)

−1.82 (0.20)

− 1.90 (0.13)

− 1.93 (0.14)

0.906

−0.04

0.194

204

Capnocytophaga sp._oral_taxon_412

N

–

− 1.89 (0.08)

−1.74 (0.18)

− 1.81 (0.12)

−2.09 (0.13)

0.173

− 0.04

0.162

205

Neisseria subflava

N

–

− 1.89 (0.09)

− 1.84 (0.18)

−2.04 (0.13)

− 1.73 (0.16)

0.267

0.10

0.118

206

Veillonella sp._oral_taxon_780

N

–

− 1.94 (0.08)

− 1.46 (0.20)

− 1.93 (0.12)

− 2.20 (0.12)

0.004

−0.10

<.001

207

Lachnospiraceae_[G-8] sp._oral_taxon_500

N

–

− 1.94 (0.07)

−1.91 (0.16)

−2.03 (0.10)

− 1.83 (0.12)

0.443

0.01

0.695

208

Capnocytophaga sp._oral_taxon_323

P

–

−1.94 (0.08)

−1.99 (0.17)

− 1.93 (0.12)

− 1.94 (0.14)

0.966

− 0.01

0.731

209

Scardovia wiggsiae

P

–

−1.94 (0.09)

− 2.07 (0.19)

− 2.11 (0.12)

− 1.66 (0.16)

0.061

0.10

0.009

210

Sphingomonas echinoides

N

–

− 1.95 (0.06)

−1.75 (0.14)

− 1.89 (0.10)

− 2.15 (0.11)

0.056

−0.10

<.001

211

SR1_[G-1] sp._oral_taxon_874

U

–

− 1.99 (0.07)

−1.76 (0.15)

− 1.88 (0.10)

−2.26 (0.11)

0.008

−0.10

0.006

212

Treponema lecithinolyticum

U

–

−2.01 (0.08)

−1.98 (0.17)

− 1.90 (0.12)

− 2.18 (0.13)

0.302

−0.10

0.068

213

Prevotella baroniae

P

–

−2.04 (0.07)

−2.20 (0.15)

− 2.03 (0.11)

− 1.96 (0.13)

0.490

0.04

0.209

214

Pseudomonas fluorescens

P

–

− 2.05 (0.07)

− 2.12 (0.15)

− 2.07 (0.11)

−1.98 (0.13)

0.767

0.03

0.334

215

Shuttleworthia satelles

P

–

− 2.08 (0.07)

− 2.27 (0.14)

− 2.21 (0.10)

−1.82 (0.12)

0.016

0.10

<.001

216

Prevotella sp._oral_taxon_306

U

 

−2.08 (0.07)

−2.32 (0.14)

− 2.21 (0.10)

−1.79 (0.13)

0.010

0.10

<.001

217

Porphyromonas sp._oral_taxon_275

N

–

− 2.11 (0.07)

−2.09 (0.16)

− 2.01 (0.12)

− 2.26 (0.12)

0.321

−0.04

0.184

218

Streptococcus sinensis

P

–

− 2.14 (0.06)

− 1.95 (0.13)

− 2.30 (0.08)

− 2.05 (0.11)

0.050

0.02

0.517

219

Anaerolineae_[G-1] sp._oral_taxon_439

N

–

− 2.14 (0.08)

− 2.47 (0.15)

− 2.22 (0.11)

−1.85 (0.14)

0.008

0.12

<.001*

220

Bacteroidaceae_[G-1] sp._oral_taxon_272

N

–

− 2.15 (0.07)

− 2.48 (0.15)

− 2.21 (0.10)

−1.87 (0.13)

0.007

0.10

<.001

221

Prevotella micans

N

–

− 2.15 (0.07)

−2.24 (0.14)

− 2.18 (0.10)

− 2.08 (0.12)

0.658

0.02

0.452

222

Leptotrichia goodfellowii

U

–

− 2.17 (0.07)

−1.90 (0.17)

−2.14 (0.11)

− 2.36 (0.12)

0.080

−0.10

0.008

223

Capnocytophaga sp._oral_taxon_903

N

–

− 2.17 (0.08)

−2.15 (0.17)

− 2.12 (0.11)

− 2.25 (0.13)

0.751

− 0.01

0.731

224

Peptostreptococcaceae_[XI][G-5] [Eubacterium]_saph

U

–

− 2.18 (0.08)

−2.46 (0.15)

− 2.13 (0.12)

− 2.08 (0.13)

0.195

0.04

0.229

225

Treponema sp._oral_taxon_237

P

–

− 2.20 (0.08)

−1.68 (0.19)

−2.21 (0.12)

− 2.46 (0.13)

0.003

−0.11

<.001*

226

Fusobacterium sp._oral_taxon_370

U

–

− 2.20 (0.06)

−2.25 (0.12)

− 2.08 (0.09)

− 2.32 (0.10)

0.176

−0.04

0.176

227

Atopobium sp._oral_taxon_199

U

–

− 2.26 (0.07)

−2.19 (0.16)

− 2.18 (0.11)

− 2.40 (0.12)

0.334

−0.02

0.433

228

Prevotella sp._oral_taxon_314

N

–

− 2.28 (0.07)

− 2.29 (0.16)

− 2.35 (0.11)

− 2.18 (0.13)

0.605

0.02

0.519

229

Capnocytophaga sp._oral_taxon_324

U

–

− 2.28 (0.07)

−2.43 (0.15)

− 2.24 (0.11)

− 2.25 (0.12)

0.588

0.03

0.256

230

Haemophilus parahaemolyticus

N

–

− 2.29 (0.08)

−1.86 (0.18)

−2.23 (0.12)

− 2.61 (0.11)

0.002

−0.11

<.001*

231

Porphyromonas sp._oral_taxon_278

U

–

− 2.29 (0.07)

−2.40 (0.14)

− 2.24 (0.11)

− 2.30 (0.12)

0.716

0.00

0.977

232

Selenomonas sp._oral_taxon_937

U

–

− 2.35 (0.06)

−2.34 (0.12)

− 2.46 (0.09)

− 2.22 (0.11)

0.203

0.03

0.386

233

Selenomonas dianae

N

–

− 2.36 (0.07)

− 2.52 (0.14)

− 2.27 (0.10)

− 2.38 (0.11)

0.367

0.02

0.569

234

Selenomonas sp._oral_taxon_133

U

–

− 2.37 (0.08)

− 2.25 (0.18)

− 2.40 (0.11)

− 2.41 (0.13)

0.719

−0.02

0.396

235

Selenomonas sp._oral_taxon_478

P

–

− 2.49 (0.06)

−2.54 (0.13)

− 2.46 (0.09)

− 2.49 (0.10)

0.882

0.03

0.306

236

Capnocytophaga sp._oral_taxon_332

U

–

− 2.50 (0.07)

−2.26 (0.16)

− 2.42 (0.11)

− 2.72 (0.11)

0.043

−0.10

0.043

237

Megasphaera sp._oral_taxon_123

N

–

− 2.51 (0.08)

− 2.06 (0.19)

− 2.51 (0.12)

− 2.77 (0.13)

0.009

− 0.10

0.002

238

Bradyrhizobium elkanii

U

–

− 2.54 (0.08)

−2.37 (0.17)

− 2.68 (0.11)

− 2.44 (0.13)

0.209

−0.00

0.900

239

Prevotella sp._oral_taxon_376

P

–

− 2.54 (0.07)

−2.22 (0.17)

− 2.49 (0.11)

− 2.79 (0.12)

0.015

−0.10

<.001

240

Prevotella sp._oral_taxon_526

P

–

− 2.56 (0.07)

−2.59 (0.14)

− 2.57 (0.10)

− 2.52 (0.12)

0.923

0.01

0.736

241

Selenomonas sp._oral_taxon_442

U

–

− 2.58 (0.05)

− 2.78 (0.11)

− 2.52 (0.09)

− 2.53 (0.09)

0.177

0.10

0.065

242

Leptotrichia sp._oral_taxon_879

U

–

− 2.60 (0.07)

− 2.56 (0.16)

− 2.62 (0.10)

−2.59 (0.11)

0.951

− 0.02

0.597

243

Selenomonas sp._oral_taxon_149

P

–

− 2.61 (0.06)

− 2.75 (0.12)

− 2.70 (0.09)

− 2.42 (0.10)

0.048

0.10

0.004

244

Aggregatibacter sp._oral_taxon_513

U

–

− 2.66 (0.07)

− 2.64 (0.14)

− 2.52 (0.11)

− 2.85 (0.11)

0.107

− 0.03

0.368

245

Treponema vincentii

N

–

− 2.67 (0.06)

−2.55 (0.13)

− 2.60 (0.09)

− 2.83 (0.09)

0.140

−0.04

0.125

246

Capnocytophaga sp._oral_taxon_380

N

–

− 2.70 (0.07)

−2.65 (0.14)

− 2.59 (0.11)

− 2.88 (0.11)

0.132

−0.10

0.107

247

Johnsonella sp._oral_taxon_166

U

–

− 2.78 (0.06)

−2.96 (0.12)

− 2.69 (0.10)

− 2.80 (0.11)

0.292

−0.01

0.855

248

Treponema medium

P

–

−2.79 (0.06)

− 2.85 (0.14)

− 2.74 (0.10)

−2.81 (0.10)

0.777

0.02

0.579

249

Fretibacterium sp._oral_taxon_358

U

–

− 2.84 (0.07)

−2.87 (0.14)

− 2.88 (0.10)

− 2.77 (0.12)

0.708

0.02

0.494

250

Neisseria pharyngis

N

–

− 2.87 (0.06)

−2.81 (0.13)

− 2.95 (0.09)

− 2.80 (0.11)

0.479

0.01

0.760

251

Prevotella sp._oral_taxon_475

N

–

− 2.87 (0.06)

−2.81 (0.12)

− 2.84 (0.09)

− 2.95 (0.09)

0.575

−0.04

0.157

252

Microbacterium flavescens

P

–

− 2.89 (0.04)

− 2.73 (0.09)

− 2.89 (0.06)

−2.97 (0.07)

0.151

−0.10

0.051

253

Mitsuokella sp._oral_taxon_521

N

–

− 2.90 (0.06)

−2.91 (0.12)

− 2.92 (0.08)

− 2.87 (0.11)

0.929

0.02

0.603

254

Lactobacillus gasseri

N

–

− 2.95 (0.06)

−3.08 (0.12)

− 3.09 (0.09)

−2.70 (0.12)

0.012

0.10

0.002

255

Butyrivibrio sp._oral_taxon_080

P

–

− 2.96 (0.06)

−2.85 (0.13)

− 2.90 (0.09)

−3.10 (0.09)

0.193

−0.10

0.038

256

Fretibacterium sp._oral_taxon_361

P

–

− 2.98 (0.06)

− 3.18 (0.10)

− 2.97 (0.09)

− 2.88 (0.11)

0.207

0.02

0.469

257

Aggregatibacter actinomycetemcomitans

P

–

− 3.01 (0.07)

−2.97 (0.15)

−3.09 (0.10)

−2.94 (0.11)

0.575

0.03

0.349

258

Streptococcus sobrinus

U

–

− 3.04 (0.06)

−3.21 (0.10)

− 3.19 (0.09)

−2.75 (0.14)

0.005

0.11

<.001*

259

GN02_[G-2] sp._oral_taxon_873

P

–

− 3.06 (0.05)

−3.08 (0.12)

− 3.03 (0.08)

− 3.10 (0.09)

0.851

−0.00

0.927

260

Prevotella multiformis

N

–

− 3.08 (0.06)

− 3.12 (0.11)

− 3.10 (0.09)

− 3.05 (0.10)

0.901

0.03

0.359

261

Brevundimonas diminuta

N

–

− 3.30 (0.04)

− 3.17 (0.09)

− 3.35 (0.06)

− 3.30 (0.07)

0.232

−0.03

0.306

262

Atopobium sp._oral_taxon_416

P

–

− 3.38 (0.05)

− 3.45 (0.09)

− 3.44 (0.07)

− 3.27 (0.09)

0.202

0.10

0.042

263

Treponema sp._oral_taxon_247

P

–

− 3.45 (0.05)

− 3.35 (0.09)

− 3.50 (0.07)

− 3.44 (0.08)

0.436

− 0.02

0.566

264

Leptothrix sp._oral_taxon_025

P

–

− 3.50 (0.04)

−3.37 (0.08)

− 3.53 (0.06)

− 3.53 (0.06)

0.216

− 0.04

0.221

265

Pyramidobacter piscolens

P

–

− 3.53 (0.04)

− 3.44 (0.10)

− 3.60 (0.06)

−3.47 (0.07)

0.251

− 0.01

0.919

266

Sphingomonas sp._oral_taxon_006

P

–

− 3.55 (0.04)

−3.49 (0.08)

− 3.60 (0.05)

− 3.52 (0.06)

0.407

− 0.00

0.989

267

Porphyrobacter tepidarius

N

–

−3.58 (0.03)

−3.51 (0.08)

− 3.65 (0.05)

−3.54 (0.06)

0.216

0.01

0.869

  1. Rank order, OTUs are sorted high to low, with most abundant OTU at the top of the table
  2. The CLR OTU is interpreted as a log [2] fold-difference for the given species relative to the overall compositional geometric mean. A mean CLR of 3 indicates a 8-fold [23] higher abundance, and a mean CLR of − 3 indicates a 8-fold lower abundance, relative to the overall compositional geometric mean
  3. SE standard error, Pearson r the Pearson product-moment correlation coefficient
  4. p-values: bolded are significant at alpha 0.05; asterisk are significant at alpha 0.05 after Bonferroni correction
  5. Culture status: N = named; U = unnamed; P = phylotyped
  6. Socransky complex32: R = red; O = orange; P = purple; G = green; Y = yellow; B = blue; −-- = not part of the Socransky classification
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BMC Oral Health

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