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Table 2 Adjusted mean difference in change from baseline in mean total DHEQ score, Schiff score and LMS scores at each time point compared to baseline (mITT population)

From: Impact of toothpaste on oral health-related quality of life in people with dentine hypersensitivity

Week comparison vs baseline Adjusted mean differencea (95% CI) p-value
Total DHEQ score Schiff score
(test teeth)
Schiff score
(all qualifying)
 
Week 4 5.89 (−1.018, 12.806)
0.0944
1.09 (0.940, 1.250)
< 0.0001
0.62 (0.533, 0.715)
< 0.0001
 
Week 8 16.99 (10.128, 23.849)
< 0.0001
1.23 (1.077, 1.383)
< 0.0001
0.71 (0.620, 0.800)
< 0.0001
 
Week 12 22.70 (15.870, 29.539)
< 0.0001
1.35 (1.198, 1.501)
< 0.0001
0.84 (0.753, 0.931)
< 0.0001
 
Week 16 27.21 (20.245, 34.165)
< 0.0001
1.40 (1.248, 1.559)
< 0.0001
0.90 (0.804, 0.986)
< 0.0001
 
Week 20 31.42 (24.464, 38.385)
< 0.0001
1.50 (1.349, 1.658)
< 0.0001
0.96 (0.864, 1.046)
< 0.0001
 
Week 24 32.55 (25.585, 39.506)
< 0.0001
1.66 (1.503, 1.812)
< 0.0001
1.09 (0.995, 1.777)
< 0.0001
 
  LMS Intensity LMS Duration LMS Tolerability LMS Description
Week 4 13.27 (9.226, 17.306)
< 0.0001
12.94 (9.111, 16.762)
< 0.0001
15.57 (12.171, 18.973)
< 0.0001
18.35 (13.850, 22.855)
< 0.0001
Week 8 17.72 (13.733, 21.704) < 0.0001 15.83 (12.054, 19.603)
< 0.0001
16.63 (13.273, 19.983)
< 0.0001
19.98 (15.536, 24.421)
< 0.0001
Week 12 20.87 (16.920, 24.829)
< 0.0001
19.07 (15.326, 22.816)
< 0.0001
20.29 (16.961, 23.619)
< 0.0001
24.32 (19.916, 28.730)
< 0.0001
Week 16 26.10 (22.051, 30.144)
< 0.0001
22.92 (19.090, 26.754)
< 0.0001
24.06 (20.652, 27.465)
< 0.0001
26.16 (21.654, 30.674)
< 0.0001
Week 20 27.74 (23.716, 31.771)
< 0.0001
25.51 (21.695, 29.323)
< 0.0001
25.55 (22.155, 28.936)
< 0.0001
28.28 (23.793, 32.771)
< 0.0001
Week 24 29.86 (25.833, 33.888)
< 0.0001
28.74 (24.930, 32.558)
< 0.0001
26.75 (23.359, 30.140)
< 0.0001
30.83 (26.341, 35.319)
< 0.0001
  1. aDifference is the baseline score minus Week score such that a positive difference shows an improvement in score; p-values in bold are significant