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Table 3 Adjusted mean change from baseline in DHEQ Section 2 scores: Total score (Q1–34), Restrictions (Q1–4), Adaptation (Q5–16), Social Impact (Q17–21), Emotional Impact (Q22–29), Identity (Q30–34), Global Oral Health rating (Q35), Effect on Life Overall (Q36–39) at each time point compared to baseline (mITT population)

From: Impact of toothpaste on oral health-related quality of life in people with dentine hypersensitivity

Week comparison vs baseline Adjusted mean differencea (95% CI) p-value
Restrictions Adaptation Social Impact Emotional Impact
Week 4 1.18 (0.108, 2.262) 0.0312 1.11 (−1.592, 3.821) 0.4185 0.57 (−0.604, 1.738) 0.3415 2.42 (0.483, 4.352) 0.0145
Week 8 2.08 (1.728, 3.866) < 0.0001 7.08 (4.391, 9.764) < 0.0001 1.77 (0.610, 2.935) 0.0029 4.42 (2.498, 6.339) < 0.0001
Week 12 3.26 (2.192, 4.322) < 0.0001 8.35 (5.674, 11.026) < 0.0001 2.42 (1.266, 3.582) < 0.0001 6.85 (4.933, 8.759) < 0.0001
Week 16 3.93 (2.844, 5.012) < 0.0001 10.43 (7.708, 13.158) < 0.0001 3.55 (2.371, 4.729) < 0.0001 7.17 (5.219, 9.115) < 0.0001
Week 20 4.15 (3.063, 5.232) < 0.0001 11.73 (9.008, 14.459) < 0.0001 4.39 (3.210, 5.568) < 0.0001 8.39 (6.438, 10.335) < 0.0001
Week 24 4.74 (3.654, 5.823) < 0.0001 11.96 (9.235, 14.686) < 0.0001 4.30 (3.119, 5.477) < 0.0001 8.67 (6.726, 10.623) < 0.0001
  Identity Global Oral Health Rating Effect on Life Overall  
Week 4 0.63 (−0.738, 1.989) 0.3676 0.09 (−0.059, 0.243) 0.2326 0.60 (0.002, 1.194) 0.0493  
Week 8 0.90 (−0.451, 2.255) 0.1907 0.07 (−0.085, 0.216) 0.3934 1.42 (0.830, 2.013) < 0.0001  
Week 12 1.81 (0.467, 3.162) 0.0085 0.13 (−0.016, 0.284) 0.0785 1.87 (1.278, 2.457) < 0.0001  
Week 16 2.12 (0.744, 3.489) 0.0026 0.14 (−0.011, 0.294) 0.0682 2.03 1.429, 2.629) < 0.0001  
Week 20 2.74 (1.371, 4.116) 0.0001 0.13 (−0.018, 0.287) 0.0844 2.34 (1.743, 2.943) < 0.0001  
Week 24 2.85 (1.477, 4.222) < 0.0001 0.18 (0.027, 0.332) 0.0211 2.34 (1.743, 2.943) < 0.0001  
  1. aDifference is the baseline score minus Week score such that a positive difference shows an improvement in score; p-values in bold are significant