Table 6 Major anomalies associated with Oral Clefts taken using the Statistical Monitoring Protocol 2012 -link EUROCAT Data Management Program (EDMP)
Major associated anomalies | CL 21 | CP 63 | |
|---|---|---|---|
n | n | ||
Anencephaly | 2 | 1 | |
Spina bifida | – | – | |
Microcephalus/Hydrocephalus | – | – | |
Absence of corpus callosum | – | 1 | |
Defects of the central nervous system (CNS) | Other brain defects (ventriculomegaly, encephalocele.etc.) | 3 | 4 |
Defects of eyes | |||
Anophthalmia/microphthalmia | 1 | 4 | |
Hypertelorism | 1 | 2 | |
Coloboma | – | 3 | |
Others | 2 | ||
Defects of ear/nose | (Low ear attachment, microtia, etc.) | 4 | 3 |
Defects of the respiratory system | (Laryngomalacia, pulmonary artery ectasia, etc.) | – | 3 |
Ventricular septal defects | – | 16 | |
Cardiovascular defects | Atrioventricular septal defects | – | 2 |
Other cardiovascular defects | 8 | 8 | |
Defects of the digestive system | Atresia, microgastria, omphalocele | 4 | – |
Defects of the urogenital system | Polycystic kidney | – | – |
Hypospadias (2nd or 3rd degree) | – | 2 | |
Cryptorchidism | – | 5 | |
Anorectal atresia/stenosis | – | 4 | |
Other urogenital defects | 1 | 6 | |
Defects of the limbs | Polydactyly/syndactyly/agenesis | 3 | 14 |
Clubfoot | 4 | 7 | |
Other congenital defects of the limbs | 4 | 4 | |
Musculoskeletal defects | (Vertebral / rib defects,craniosynostosis, dysplasia, etc.) | 1 | 5 |
Defects of the integument | Cystic hygroma, hypoplasia cutis | – | 1 |