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Table 1 5-ALA triggered OSCC cells to produce protoporphyrin IX (\( \overline{x}\pm s \), × 103)

From: An in vitro study of the effect of 5-ALA-mediated photodynamic therapy on oral squamous cell carcinoma

Group (5-ALA)

2 h

4 h

6 h

12 h

24 h

Blank

0.007 ± 0.001

0.005 ± 0.001

0.008 ± 0.002

0.018 ± 0.003

0.026 ± 0.003

5 mg/L

0.238 ± 0.006*

0.361 ± 0.012*

0.351 ± 0.017*

0.693 ± 0.037*#

2.673 ± 0.048#

10 mg/L

0.612 ± 0.061*

0.816 ± 0.028*

0.735 ± 0.123*#

1.487 ± 0.067*#

5.432 ± 0.079*#

25 mg/L

2.557 ± 0.161*

3.212 ± 0.037*

5.721 ± 0.483*#

11.987 ± 0.654*#

16.987 ± 2.391*#

50 mg/L

4.962 ± 0.127*

7.791 ± 0.263*

11.723 ± 1.273*#

21.076 ± 0.763*#

27.473 ± 3.473*#

100 mg/L

7.643 ± 1.673*

11.376 ± 2.065*#

14.723 ± 1.238*#

26.753 ± 2.632*#

32.763 ± 3.973*#

150 mg/L

8.124 ± 1.721*

12.451 ± 2.376*#

16.302 ± 1.098*#

29.876 ± 2.398*#

33.902 ± 4.872*#

  1. The sample size at each time point was 3 in each group; compared with the blank group at the same time point, *P < 0.05; compared with the same group after 2 h, #P < 0.05