Table 1 The basic information and data of 13 studies in the meta-analysis
First author/Year | Country | Ethnicity | Study design | Source of | Genotyping | Study size | P for HWE | Case | Control | Case | Control |
|---|---|---|---|---|---|---|---|---|---|---|---|
Controls | method | case/control | in controls | CC/CT/TT | CC/CT/TT | C/T | C/T | ||||
Enmin Huang 2012 [9] | China | East Asian | Case-control | PB | Mass spectrometry | 300/354 | 0.689 | 33/149/118 | 70/179/105 | 215/385 | 319/389 |
Lang Feifei 2017 [10] | China | East Asian | Case-control | PB | TaqMan | 162/178 | > 0.05 | 43/69/50 | 22/85/71 | 155/169 | 129/227 |
Xiaoqing Yin 2018 [6] | China | East Asian | Case-control | PB | TaqMan | 1278/1295 | 0.331 | 202/606/458 | 270/640/374 | 1010/1522 | 1180/1388 |
Zhongwei Z 2013 [11] | China | East Asian | Case-control | PB | PCR-RFLP | 369/433 | 0.99 | 62/162/49 | 145/211/77 | 286/260 | 501/365 |
Pan 2011 [12] | China | East Asian | Case-control | HB | PCR | 367/382 | 0.26 | 50/159/158 | 89/202/91 | 259/475 | 380/384 |
Mi 2014 [13] | China | East Asian | Case-control | HB | Mini-sequencing | 324/343 | 0.956 | 78/162/84 | 63/168/112 | 318/330 | 294/392 |
Sun 2015 (I) [14] | China | East Asian | Case-control | PB | Affymetrix Genome-Wide | 504/455 | 0.991 | 77/250/203 | 110/258/151 | 404/656 | 478/560 |
Sun 2015(II) [14] | China | East Asian | Case-control | PB | Affymetrix Genome-Wide | 384/793 | 0.977 | 74/189/121 | 185/399/216 | 337/431 | 769/831 |
Gurramkond 2015 [5] | Indian | India’s | Case-control | HB | KASPar | 173/176 | 0.85 | 4/65/75 | 20/77/79 | 73/215 | 117/235 |
Reiter 2015 [15] | Germany | Caucasian | Case-control | PB | PCR | 119/383 | 0.843 | 20/46/53 | 46/176/161 | 86/152 | 268/498 |
Clarissa Fontoura 2012 [16] | Brazil | Caucasian | Case-control | HB | TaqMan | 400/412 | 0.51 | 38/165/182 | 42/180/166 | 241/529 | 264/512 |
Kerstin U.Ludwig 2014 [8] | Mexico | Mayan | Case-control | PB | PCR-RFLP | 153/337 | 0.192 | 15/67/66 | 51/139/129 | 97/199 | 241/397 |
Do Rego Borges 2015 [7] | Brazil | Brazilian | Case-control | PB | PCR | 293/352 | 0.964 | 29/100/164 | 25/137/190 | 158/428 | 187/517 |
Butali 2011 [17] | Nigerian | African | Case-control | PB | PCR | 88/88 | 0.88 | 54/30/4 | 47/35/6 | 138/38 | 129/47 |