Fig. 3
From: Melatonin antagonizes lipopolysaccharide-induced pulpal fibroblast responses
Expression of melatonin receptors MT1 and MT2 in normal and inflamed pulps. 3A and 3D show H&E staining of normal and inflamed pulp under 200X magnification level, respectively. 3B and 3C illustrate MT1 and MT2 staining in normal pulps, whereas 3E and 3F show MT1 and MT2 expression profiles in inflamed pulp. In normal healthy pulps, both MT1 and MT2 were intensely expressed in odontoblastic layer and cell-rich zones. Co-localization of MT1 and MT2 with pulpal fibroblasts was observed in pulpal stroma (arrow heads; 3B and 3C). In inflamed pulp, increased vascularization (arrows; 3D) and leukocyte infiltration (bold arrows; 3D) were seen in pulpal stroma. Similar to normal healthy pulps, MT1 and MT2 were found in odontoblastic layers (arrows; 3E and 3F) and co-localized with infiltrating leukocytes located in the pulp core (bold arrows; 3E and 3F)