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Table 3 The comparison of IL-1β, CXCL8, and TNF-α levels in patients’ groups

From: Analysis of IL-1β, CXCL8, and TNF-α levels in the crevicular fluid of patients with periodontitis or healthy implants

  Control (I; n = 36) Mild periodontitis (II; n = 48) Moderate periodontitis (III; n = 43) Severe periodontitis (IV; n = 30) Implant (V; n = 32)
IL-1β (pg/mL)
Mean ± SD 16.90 ± 18.65 36.16 ± 33.98 46.76 ± 38.62 61.04 ± 41.41 23.73 ± 27.07
Range 0.10–77.90 0.10–156.80 0.10–181.90 6.40–153.80 0.10–125.70
CXCL8 (pg/mL)
Mean ± SD 37.91 ± 34.06 44.10 ± 38.05 58.16 ± 55.26 51.94 ± 45.87 40.90 ± 56.63
Range 3.20–132.20 0.90–205.20 4.90–274.30 2.50–185.20 3.10–296.30
TNF-α (pg/mL)
Mean ± SD 4.31 ± 2.02 4.56 ± 2.15 5.41 ± 2.12 5.34 ± 2.39 5.71 ± 1.94
Range 0.10–9.10 0.10–10.20 1.30–9.50 1.20–11.20 1.50–9.40
  1. The Mann–Whitney U test was performed to analyzed differences in the levels of IL-1β, CXCL8, and TNF-α in GCF/PISF. Statistical significance was set at p = 0.05