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Table 6 GRADE summary of findings

From: Factors influencing an eruption of teeth associated with a dentigerous cyst: a systematic review and meta-analysis

Admission type No. of studies Study design Risk of bias Inconsistency Indirectness Imprecision Other considerations RR (95% CI) Certainty
Certainty assessment
RR (risk ratio) for spontaneous eruption of the teeth 4 Retrospective cohort studies Serious Seriousa Not serious Seriousb None 2.608 Very low
D (mean difference) for mean age 4 Retrospective cohort studies Serious Seriousa Not serious Seriousb None NR Very low
RR (risk ratio for root formation) 3 Retrospective cohort studies Serious Seriousa Not serious Seriousb None 2.106 Very low
D (mean difference) for cusp depth 3 Retrospective cohort studies Serious Seriousa Not serious Seriousb None NR Very low
D (mean difference) for angulation 4 Retrospective cohort studies Serious Seriousa Not serious Seriousb None NR Very low
D (mean difference) for cyst area 2 Retrospective cohort studies Serious Seriousa Not serious Seriousb None NR Very low
D (mean difference) for space/tooth size 4 Retrospective cohort studies Serious Seriousa Not serious Seriousb None NR Very low
  1. GRADE, Grading of Recommendations Assessment, Development, and Evaluation; RR, risk ratio; CI, confidence level; NR, not reported
  2. aDifferent sample sizes and timings of studies lead to inconsistency in the results
  3. bVery few studies published which raises the suspicion of publication bias
  4. GRADE quality of evidence: High quality: We are very confident that the true effect lies close to that of the estimate of the effect. Moderate quality: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different. Low quality: Our confidence in the effect estimate is limited. The true effect may be substantially different from the estimate of the effect. Very low quality: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect